摘要
目的 系统分析环境铅暴露与儿童青少年血压之间的关联。方法 系统检索中国知网、万方、PubMed、Embase、Web of Science和Cochrane library 6个数据库中有关环境铅暴露对儿童青少年血压影响的研究,提取相关数据进行Meta分析,计算β值以及95%CI,对环境铅暴露与儿童青少年血压的关联进行系统化评价。结果 经过合并效应分析后发现,孕期及儿童青少年时期的铅暴露与儿童青少年收缩压呈正相关。结论 孕期及儿童青少年时期的铅暴露可能与儿童青少年收缩压升高存在关联。
Objective To explore the associations between environmental lead exposure and blood pressure among children and adolescents.Methods Studies on the effects of environmental lead exposure on blood pressure among children and adolescents were systematically searched from six databases:Chinese National Knowledge Infrastructure(CNKI),Wang Fang,PubMed,Embase,Web of Science and Cochrane library.The relevant data were extracted for meta-analysis and integration.Beta values as well as 95%CIs were calculated to systematically evaluate the associations between environmental lead exposure and blood pressure.Results After combined effects analysis,metallic lead exposure during pregnancy and childhood and adolescence was positively associated with systolic blood pressure among children and adolescents.Conclusion Lead exposure during pregnancy and childhood and adolescence may be associated with elevated systolic blood pressure among children and adolescents.
作者
邓曼馨
龚茁
向仕婷
仇君
DENG Manxin;GONG Zhuo;XIANG Shiting;QIU Jun(College of Public Health,Changsha Medical University,Changsha 410219,Hunan,China;Institute of Pediatric Medicine,Hunan Children’s Hospital,Changsha 410007,Hunan,China)
出处
《中国校医》
2025年第3期200-203,216,共5页
Chinese Journal of School Doctor
基金
湖南省自然科学基金(2023JJ30319)。
关键词
儿童青少年
环境暴露
金属铅
血压
META分析
Children and adolescents
Environmental exposure
Metallic lead
Blood pressure
Meta-analysis
