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口服阿奇霉素联合布地奈德、特布他林雾化吸入治疗小儿支原体肺炎的临床效果

Clinical Effect of Oral Azithromycin Combined with Budesonide and Terbutaline Nebulized Inhalation in Treatment of Mycoplasma Pneumoniae Pneumonia in Children
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摘要 目的:分析支原体肺炎患儿采取阿奇霉素(口服)联合布地奈德、特布他林雾化吸入治疗的效果。方法:将信宜市妇幼保健院2022年6月—2024年5月收治的支原体肺炎患儿80例纳入研究,采取随机数字表法分为两组,各40例。除常规治疗外,常规组口服阿奇霉素治疗,联合组采取阿奇霉素(口服)联合布地奈德、特布他林雾化吸入治疗。对比两组治疗效果。结果:联合组治疗总有效率高于常规组(P=0.025);相较于常规组,联合组疾病症状消失时间更早,住院时间更短(P<0.001)。治疗后,两组C反应蛋白(CRP)、降钙素原(PCT)水平均改善,相较于常规组,联合组CRP、PCT水平更低(P<0.001);两组不良反应发生率比较,未见明显差异(P>0.05)。结论:支原体肺炎患儿采取阿奇霉素(口服)联合布地奈德、特布他林雾化吸入治疗的效果较佳,能够降低炎性因子水平,促进患儿康复,保证治疗安全性。 Objective:To analyze the effect of azithromycin(oral)combined with budesonide and terbutaline nebulized inhalation treatment in children with Mycoplasma pneumonia.Methods:A total of 80 children with Mycoplasma pneumonia admitted to Xinyi Maternal and Child Health Hospital from 2022 to 2024 were analyzed.80 cases of children with mycoplasma pneumonia admitted to Xinyi Maternal and Child Health Hospital from June 2022 to May 2024 were included in the study,and they were divided into two groups of 40 cases each by adopting the method of randomized numerical table.In addition to conventional treatment,the conventional group was treated with oral azithromycin,and the combined group was treated with azithromycin(oral)combined with budesonide and terbutaline nebulized inhalation.Compare the treatment effect of the two groups.Results:The total effective rate of treatment in the combined group was higher than that in the conventional group(P=0.025);compared with the conventional group,the symptoms of the disease disappeared earlier and the hospitalization time was shorter in the combined group(P<0.001).After treatment,the levels of C-reactive protein(CRP)and procalcitonin(PCT)improved in both groups,and the levels of CRP and PCT were lower in the combined group compared with those in the conventional group(P<0.001);the incidence rates of adverse reactions in the two groups did not show any significant difference(P>0.05).Conclusion:Azithromycin(oral)combined with budesonide and terbutaline nebulized inhalation treatment for children with mycoplasma pneumonia is more effective,can reduce the level of inflam.
作者 刘成 刘国才 Liu Cheng;Liu Guocai(Xinyi Maternal and Child Health Hospital,Xinyi 525300,Guangdong Province,China)
出处 《中国社区医师》 2025年第15期7-9,共3页 Chinese Community Doctors
关键词 小儿 支原体肺炎 阿奇霉素 布地奈德 特布他林 Children Mycoplasma pneumoniae pneumonia Azithromycin Budesonide Terbutaline
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