摘要
目的 探讨胺碘酮+普罗帕酮对急诊快速性心律失常患者心功能的改善效果。方法 84例急诊快速性心律失常患者,按照随机数字表法分成观察组和对照组,每组42例。对照组予以胺碘酮单一治疗,观察组予以胺碘酮+普罗帕酮治疗。比较两组患者心功能指标[左室射血分数(LVEF)、左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)]、治疗效果、心率、血液流变学指标、生活质量。结果 治疗后,两组心率均较治疗前降低,且观察组心率(83.02±12.40)次/min明显低于对照组的(95.20±11.48)次/min(P<0.05)。治疗后,两组LVEF均较治疗前升高, LVEDD、LVESD均较治疗前缩短,且观察组LVEF(52.47±6.34)%比对照组的(49.25±6.42)%更高, LVEDD(43.29±5.78)mm、LVESD(30.43±5.27)mm比对照组的(46.87±5.66)、(33.58±5.41)mm更短(P<0.05)。治疗后,两组血浆粘度、全血高切粘度均较治疗前下降,且观察组血浆粘度(1.12±0.33)mPa·s、全血高切粘度(3.02±0.85)mPa·s比对照组的(1.36±0.42)、(3.46±0.95)mPa·s更低(P<0.05)。观察组治疗总有效率97.62%比对照组的85.71%更高(P<0.05)。治疗后,两组生活质量评分均较治疗前升高,且观察组生活质量评分(92.28±2.59)分比对照组的(88.31±2.37)分更高(P<0.05)。结论 应用胺碘酮+普罗帕酮能更好地提高急诊快速性心律失常患者的心功能水平,对患者的康复有积极的意义。
Objective To explore the effect of amiodarone+propafenone on the improvement of cardiac function in patients with tachyarrhythmia in emergency.Methods 84 patients with tachyarrhythmia in emergency were divided into an observation group and a control group according to the random numerical table,with 42 cases in each group.The control group was treated with amiodarone alone,while the observation group was treated with amiodarone+propafenone.Patients in both groups were compared in terms of cardiac function indicators[left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD)],therapeutic effects,heart rate,hemorheological indicators and quality of life.Results After the treatment,the heart rates in both groups decreased compared with before the treatment,and the heart rate of(83.02±12.40)beats/min in the observation group was significantly lower than(95.20±11.48)beats/min in the control group(P<0.05).After the treatment,LVEF in both groups increased compared with before the treatment,and LVEDD and LVESD were shortened compared with before the treatment;the observation group had a higher LVEF of(52.47±6.34)%than(49.25±6.42)%in the control group;the observation group had LVEDD of(43.29±5.78)mm and LVESD of(30.43±5.27)mm,which were shorter than(46.87±5.66)and(33.58±5.41)mm in the control group(P<0.05).After the treatment,the plasma viscosity and whole blood high-shear viscosity in both groups decreased compared with before the treatment;the plasma viscosity in the observation group was(1.12±0.33)mPa·s and the whole blood high-shear viscosity was(3.02±0.85)mPa·s,which were lower than(1.36±0.42)and(3.46±0.95)mPa·s in the control group(P<0.05).The total effective rate of treatment in the observation group was 97.62%,which was higher than 85.71%in the control group(P<0.05).After the treatment,the quality of life scores in both groups increased compared with before the treatment,and the quality of life score of(92.28±2.59)points in the observation group was higher than(88.31±2.37)points in the control group(P<0.05).Conclusion The application of amiodarone combined with propafenone can better improve the cardiac function level of patients with emergency tachyarrhythmia,which has a positive significance for the rehabilitation of patients.
作者
高继胜
董蕾
GAO Ji-sheng;DONG Lei(Emergency Medicine Department,The 970th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army,Yantai 264000,China)
出处
《中国实用医药》
2025年第13期6-9,共4页
China Practical Medicine
关键词
胺碘酮
普罗帕酮
急诊快速性心律失常
心功能
Amiodarone
Propafenone
Tachyarrhythmia in emergency
Cardiac function
