摘要
目的本研究旨在探讨酒精性精神障碍患者(alcohol-induced psychotic disorder,AIPD)与单纯酒依赖患者(uncomplicated alcohol dependence,UAD)在冲动性和认知功能方面的差异。方法选取2019年1月至2021年10月期间在深圳市康宁医院成瘾病房住院的93名酒依赖患者,其中AIPD组35名,UAD组58名。使用Barratt-11冲动性量表(Barratt-11 Impulsivity Scale,BIS-11)、蒙特利尔认知量表(Montreal Cognitive Assessment,MOCA)评估患者的冲动性和认知功能,同时收集研究对象的一般资料和临床特征资料。结果AIPD组的无计划冲动与UAD组相比,具有统计学意义(P=0.028)。AIPD组在视空间与执行功能(P=0.017)、命名(P=0.033)、注意(P=0.024)和延迟回忆(P=0.027)方面与UAD组的差异有统计学意义。无计划冲动和认知功能中的视空间与执行功能、注意、抽象和总分存在显著正相关;注意冲动与视空间和执行功能存在显著正相关。冲动总分与视空间与执行功能、抽象以及MOCA总分存在显著正相关。结论有精神病性症状的酒依赖患者相较于单纯酒依赖患者,表现出较低的无计划冲动性和更明显的认知功能损伤,并且冲动性和认知功能之间存在相关性。因此,在患者的治疗和康复过程中需要特别关注这些特征。
Objective To explore the differences in impulsivity and cognitive function between patients with Alcoholinduced psychotic disorder(AIPD)and those with uncomplicated alcohol dependence(UAD).Methods We selected 93 alcohol-dependent patients who were hospitalized in the Department of Addiction Medicine of Shenzhen Kangning Hospital from January 2019 to October 2021,including 35 in the AIPD group and 58 in the UAD group.We used the Positive and Negative Syndrome Scale(PANSS),Barratt-11 Impulsivity Scale(BIS-11),and Montreal Cognitive Assessment(MOCA)to assess the patients'mental symptoms,impulsivity,and cognitive function.We also collected general information and clinical characteristics of the study subjects.Results The AIPD group exhibited statistically significant differences in unplanned impulsivity compared to the UAD group(P=O.028).The AIPD group showed statistically significant differences in visual space and executive function(P=0.017),naming(P=0.033),attention(P=0.024),and delayed recall(P=0.027)compared to the UAD group.There were significant positive correlations between unplanned impulsivity and visual space and executive function,attention,abstraction and the total score of cognitive function.There was a significant positive correlation between attentional impulsivity and visual space and executive function.The total score of impulsivity was positively correlated with visual space and executive function,abstraction and the total score of MOCA.Conclusion Alcohol-dependent patients with psychotic symptoms demonstrate lower unplanned impulsivity and more pronounced cognitive impairment compared to those with uncomplicated alcohol dependence.And there is a correlation between impulsivity and cognitive function.Therefore,special attention should be paid to these features during the treatment and rehabilitation process of patients.
作者
刘晓颖
黄庚娣
贾晓健
杨纪辉
孔志
刘雨
刘毅
杨梅
LIU Xiao-ying;HUANG Geng-di;JIA Xiao-jian;YANG Ji-hui;KONG Zhi;LIU Yu;LIU Yi;YANG Mei(Shenzhen Mental Health Center/Shenzhen Kangning Hospital,Shenzhen 518020,Guangdong,China)
出处
《中国药物依赖性杂志》
2025年第2期133-137,共5页
Chinese Journal of Drug Dependence
基金
国家重点研发计划项目(2018YFC1314400)
广东省高水平临床重点专科(深圳市配套建设经费)资助(SZGSP013)。
关键词
酒精性精神障碍
单纯酒依赖
冲动性
认知功能
alcohol-induced psychotic disorders
uncomplicated alcohol dependence
impulsivity
cognitive function
