摘要
慢性前列腺炎、前列腺增生以及勃起功能障碍已经成为影响中国男性生命质量的三大重要男科疾病。八髎穴位于人体骶部,络肾属膀胱,连通冲、任、督三脉,故八髎穴既能调节肾与膀胱二经,又可同时调节督、任、冲三脉气血,以治疗男性生殖系统疾病。针灸八髎穴可以明显改善男科疾病患者临床症状,提高患者生命质量。回顾近年来国内外有关男科疾病的发病机制和针刺八髎穴治疗男科疾病的研究,发现针灸八髎穴可能通过骶神经转导信号从而提高海绵体内压、收缩前列腺平滑肌以及兴奋骶髓排尿中枢,同时通过调节炎症介质、抑制免疫反应、激活下丘脑-垂体-性腺轴以及改善生殖系统血流变学等多途径达到治疗男科疾病的作用。尽管针灸八髎穴治疗男科疾病的临床和作用机制研究已取得一定进展,但针灸八髎穴治疗男科疾病的机制仍需深入探索,为寻找更为特异和有效的治疗靶点提供实验依据和理论基础,从而推动八髎穴在男性生殖系统疾病临床上的广泛应用。
Chronic prostatitis,benign prostatic hyperplasia,and erectile dysfunction have become three major and prevalent andrological disorders that significantly affect the quality of life of Chinese men.Eight Liao acupoints,located in the sacral region,are connected to the kidney and bladder meridians and intersect with the thoroughfare,conception,and governor vessels.Therefore,acupuncture and moxibustion at eight Liao acupoints can regulate both the kidney and bladder meridians as well as harmonize the qi and blood of the thoroughfare,conception,and governor vessels,making it effective in treating male reproductive system disorders.Clinical studies have shown that acupuncture and moxibustion at the eight Liao acupoints can significantly alleviate symptoms of andrological conditions and improve patients′quality of life.A review of recent studies in China and abroad on the pathogenesis of andrological diseases and acupuncture treatment at the eight Liao acupoints suggests that acupuncture and moxibustion at the eight Liao acupoints may work through sacral nerve signal transduction to increase intracavernosal pressure,contract prostatic smooth muscle,and activate the sacral micturition center.Additionally,it may exert therapeutic effects by regulating inflammatory mediators,inhibiting immune responses,activating the hypothalamic-pituitary-gonadal axis,and improving hemorheology in the reproductive system.Although notable progress has been made in clinical and mechanistic research on acupuncture and moxibustion at the eight Liao acupoints for andrological diseases,the mechanisms in treating andrological diseases remain to be further explored.This is expected to provide experimental evidence and theoretical support for identifying more specific and effective therapeutic targets,thereby promoting the broader clinical application of eight Liao acupoints in male reproductive system disorders.
作者
张维维
晏明熙
薛凯阳
崔瑾
闫安
车邦威
ZHANG Weiwei;YAN Mingxi;XUE Kaiyang;CUI Jin;YAN An;CHE Bangwei(College of Acupuncture-Moxibustion and Tuina,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China;Department of Acupuncture and Moxibustion,The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550001,China;Department of Urology,The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550001,China)
出处
《世界中医药》
北大核心
2025年第6期1032-1037,共6页
World Chinese Medicine
基金
国家自然科学基金项目(82360971)——针刺通过调控VEGF及PI3K/Akt/eNOS信号通路治疗勃起功能障碍的机制研究。
关键词
八髎穴
针灸
男科疾病
骶神经
盆底肌痉挛
生殖微循环
临床应用
机制研究
Eight Liao acupoints
Acupuncture and moxibustion
Andrological diseases
Sacral nerves
Pelvic floor muscle spasm
Reproductive microcirculation
Clinical application
Mechanism research
