摘要
我国是生猪养殖和猪肉消费第一大国,养殖量和消费量均占全球一半以上,猪肉占我国肉类消费的60%。疾病是影响生猪产业健康发展的重要因素。针对猪场传染性疾病防控,可以从病原体的角度开发疫苗和药物,也可以从宿主(猪)遗传角度发掘抗性基因,培育抗病猪新品系(种)。对于疫苗效果不理想或无疫苗的重大传染性疾病(蓝耳病、非洲猪瘟),借助生物育种技术如基因编辑培育抗病猪有望从根本上解决这些疾病的防控及其对养猪业造成的经济损失。本文主要围绕目前我国在猪病领域开展的抗病育种工作进行综述,以期为我国猪场疫病防控、培育战略性新品种以及实现种业科技自立自强提供基础,同时对猪抗病育种领域未来发展趋势进行展望。
China is the largest country in pig breeding and pork consumption,with breeding volume and consumption accounting for more than half of the world,and pork accounts for 60%of China's meat consumption.The disease is an important factor affecting the healthy development of the pig industry worldwide.To prevent and control infectious diseases in pig farms,we can develop vaccines and drugs from the perspective of pathogens.We also can explore resistance genes from the genetic perspective of the host(pig)to breed new strains(species)of disease-resistant pigs.For the major infectious diseases(such as PRRS and ASF)for which vaccine efficacy is not ideal or vaccines are not available,breeding diseaseresistant pigs with biological breeding technology is expected to fundamentally solve the prevention and control of these diseases and the economic losses caused to the pig industry.In this review,we mainly focuses on the disease resistance breeding work carried out in the field of swine disease in China,with a view to providing a basis for the prevention and contr ol of swine disease in China,cultivating strategic new breeds,and achieving the self-reliance and self-improvement of the seed industry;at the same time,it also gives an outlook on the future development trend of the field of swine disease resistance breeding.
作者
郭春和
陈永杰
张晓晓
张春红
焦茂兴
GUO Chunhe;CHEN Yongjie;ZHANG Xiaoxiao;ZHANG Chunhong;JIAO Maoxing(Guangdong Laboratory for Lingnan Modern Agriculture,College of Veterinary Medicine,South China Agricultural University,Guangdong Guangzhou 510642,China;Animal Disease Prevention and Control Center in Zhaoqing,Guangdong Zhaoqing 526000,China;College of Life Sciences Resources and Environment,Yichun University,Jiangxi Yichun 336000,China)
出处
《中国畜牧杂志》
北大核心
2025年第4期61-68,共8页
Chinese Journal of Animal Science
基金
广州市科技计划项目(2023B03J0947、2025D04J 0072)
国家重点研发计划项目(2023YFD1801500)
岭南现代农业科学与技术广东省实验室自主项目(NG2022003)。
关键词
猪
抗病育种
基因编辑
抗性基因
Pigs
Breeding for disease resistance
Gene-editing
Resistance genes
