摘要
研究旨在了解广西野生猕猴甲型肝炎病毒(HAV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和戊型肝炎病毒(HEV)感染情况。采用酶联免疫吸附试验(ELISA)对广西某自然保护区67只野生猕猴血清样本进行HAV-免疫球蛋白M(IgM)抗体、HEV-IgM抗体、HCV抗体和HBV表面抗原(HBsAg)检测,采用PCR荧光探针法检测血清样本HAV、HBV、HCV和HEV核酸。结果显示,HBsAg及HCV抗体均为阴性,HAVIgM抗体、HEV-IgM抗体阳性率分别为1.49%(1/67)、4.48%(3/67);未检出HAV、HBV、HCV核酸,HEV核酸阳性率为1.49%(1/67)。研究表明,广西野生猕猴可感染或携带HAV、HEV,未检出HBV、HCV阳性个体。
This study aimed to investigate the prevalence of hepatitis A virus(HAV),hepatitis B virus(HBV),hepatitis C virus(HCV),and hepatitis E virus(HEV)infections in wild macaques in Guangxi.Serum samples from 67 wild macaques in a Guangxi nature reserve were tested for HAV-immunoglobulin M(IgM)antibodies,HEV-IgM antibodies,HCV antibodies,and HBV surface antigen(HBsAg)using enzyme-linked immunosorbent assay(ELISA).Nucleic acids of HAV,HBV,HCV,and HEV were detected using PCR fluorescent probe assays.Results showed that HBsAg and HCV antibodies were all negative.The positive rates for HAV-IgM and HEV-IgM antibodies were 1.49%(1/67)and 4.48%(3/67),respectively.No HAV,HBV,or HCV nucleic acids were detected,while HEV nucleic acid positivity was 1.49%(1/67).The study indicates that wild macaques in Guangxi can be infected with or carry HAV and HEV,but no HBV or HCV positive individuals were detected.
作者
侯江宁
张陆娟
曾奇
胡莉萍
隆丽梅
许宾达
陈钦艳
Hou Jiangning;Zhang Lujuan;Zeng Qi;Hu Liping;Long Limei;Xu Binda;Chen Qinyan(Nanning Wild Animals and Plants Protection Station,Guangxi Nanning 530021;Guangxi Center for Disease Control and Prevention,Guangxi Key Laboratory for the Prevention and Control of Viral Hepatitis,Guangxi Nanning 530028;Guangxi Mount Longhu Nature Reserve Management Office,Guangxi Nanning 532700)
出处
《现代畜牧兽医》
2025年第3期63-65,共3页
Modern Journal of Animal Husbandry and Veterinary Medicine
基金
国家自然科学基金项目(81703283)
广西壮族自治区疾病预防控制中心青年科技工作者科研课题项(202402)。
