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基层糖尿病高风险人群血管硬化程度的现状及PWV评估的可行性研究

The Current Situation of Vascular Sclerosis and the Feasibility of PWV Assessment in Grassroots Diabetes High Risk Population
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摘要 目的本研究旨在调查基层人群的血管硬化程度现状,并探讨脉搏波传导速度(PWV)在早期评估糖尿病高风险人群动脉弹性中的可行性。方法采用无创动脉硬化检测设备,测量203例糖尿病高风险人群和315例糖尿病低风险人群的踝动脉PWV(脉搏波传导速度)和随机血糖水平,并绘制ROC曲线。结果糖尿病高风险组的PWV参数和随机血糖水平显著高于低风险组(p<0.001)。ROC曲线下面积为0.739,特异度为86.72%,敏感度为62.6%。结论糖尿病高风险人群在早期即表现出动脉弹性降低,踝动脉PWV可作为早期定量评估血管僵硬度的有效工具。 Objective This study aims to investigate the current situation of vascular sclerosis in the grass-roots population,and to explore the feasibility of pulse wave velocity(PWV)in the early assessment of arterial elasticity in high-risk diabetes population.Method The ankle artery PWV(pulse wave velocity)and random blood glucose levels were measured in 203 high-risk diabetes patients and 315 lowrisk diabetes patients with non-invasive arteriosclerosis detection equipment,and the ROC curve was drawn.Result PWV parameters and random blood glucose levels in the high-risk group of diabetes were significantly higher than those in the low-risk group(p<0.001).The area under the ROC curve is 0.739,the specificity is 86.72%,and the sensitivity is 62.6%.Conclusion The high risk population of diabetes shows a decrease in arterial elasticity at an early stage,and ankle artery PWV can be an effective tool for early quantitative assessment of vascular stiffness.
作者 何梦玲 蓝俊康 周佩如 杨心茹 朱瑶瑶 丘妍 Mengling He;Junkang Lan;Peiru Zhou;Xinru Yang;Yaoyao Zhu;Yan Qiu(Jinan University Affiliated Fifth Hospital(Shenhe People's Hospital,Heyuan City),Heyuan,Guangdong 517000)
出处 《医学研究前沿》 2025年第1期13-15,共3页 Frontiers of Medical Research
基金 2022年市社会发展科技计划项目(指导性项目)。
关键词 糖尿病高风险人群 动脉硬化 脉搏波传导速度 diabetes high-risk population arteriosclerosis PWV
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