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中老年住院良性前列腺增生患者血糖和血脂代谢异常的研究 被引量:1

The Study of Abnormal Blood Glucose and Lipid Metabolism in Middle-Aged and Elderly Hospitalized Patients With Benign Prostatic Hyperplasia
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摘要 目的 探讨中老年住院良性前列腺增生患者血糖和血脂代谢异常的影响。方法 选取2022年1月—2023年12月南雄市人民医院收治的中老年住院良性前列腺增生患者100例作为观察组,并选取同时间段100例健康体检人群作为对照组。2组均行血糖(空腹血糖、餐后2 h血糖)、血脂(总胆固醇、甘油三酯)以及良性前列腺增生相关指标(前列腺体积、国际前列腺症状评分)检测,并比较2组间的差异。根据观察组患者的国际前列腺症状评分结果分为轻症组(评分为0~7分)、中症组(8~19分)、重症组(≥20分)3组,比较3组的血糖、血脂以及疾病相关指标的差异,最后通过Pearson相关性法分析中老年住院良性前列腺增生患者血糖、血脂指标与前列腺体积的相关性。结果 (1)观察组的空腹血糖、餐后2 h血糖、总胆固醇、甘油三酯、前列腺体积以及国际前列腺症状评分均高于对照组,差异有统计学意义(P <0.05)。(2)重症组的空腹血糖、餐后2 h血糖、总胆固醇、甘油三酯、前列腺体积以及国际前列腺症状评分均高于轻症组、中症组,差异有统计学意义(P <0.05);且中症组的空腹血糖、餐后2 h血糖、总胆固醇、甘油三酯、前列腺体积以及国际前列腺症状评分均高于轻症组,差异有统计学意义(P <0.05)。(3)通过Pearson相关性分析发现,中老年住院良性前列腺增生患者的空腹血糖、餐后2 h血糖、总胆固醇、甘油三酯与前列腺体积、国际前列腺症状评分存在正相关性(P <0.05)。结论 中老年住院良性前列腺增生患者血糖和血脂代谢异常程度与病情严重程度存在正相关性,因此可以通过检测患者的血糖、血脂水平评估患者的病情状况,从而为临床治疗提供有效指导依据。 Objective To explore the influence of abnormal blood glucose and lipid metabolism in middle-aged and elderly hospitalized patients with benign prostatic hyperplasia.Methods A total of 100 middle-aged and elderly hospitalized patients with benign prostatic hyperplasia from January 2022 to December 2023 of Nanxiong People′s Hospital were selected as the observation group,and 100 healthy subjects in the same period of time were selected as the control group.Blood glucose(fasting blood glucose,2 h postprandial blood glucose),blood lipid(total cholesterol,triglyceride)and BPH related indicators(prostate volume,international prostate symptom score)were detected in both groups,and the differences between the two groups were compared.Then,according to the results of international prostate symptom score,patients in the observation group were divided into three groups:mild group(0-7 points),moderate group(8-19 points)and severe group(≥20 points),and the differences of blood sugar,blood lipids and disease-related indicators among the three groups were compared.Finally,Pearson correlation method was used to analyze the correlation between blood glucose,blood lipids and prostate volume in middle-aged and elderly hospitalized patients with BPH.Results(1)The fasting blood glucose,postprandial 2-hour blood glucose,total cholesterol,triglycerides,prostate volume,and International prostate symptom score in the observation group were all higher than those in the control group,and the differences were statistically significant(P<0.05).(2)Fasting blood glucose,postprandial 2-hour blood glucose,total cholesterol,triglycerides,prostate volume,and international The prostate symptom score was higher in both the mild and moderate symptom groups,and the difference was statistically significant(P<0.05).The fasting blood glucose,postprandial 2-hour blood glucose,total cholesterol,triglycerides,prostate volume,and International prostate symptom scorein the moderate group were all higher than those in the mild group,and the differences were statistically significant(P<0.05).(3)By Pearson correlation analysis,fasting blood glucose,2 h postprandial blood glucose,total cholesterol and triglyceride were positively correlated with prostate volume and international prostate symptom score in middle-aged and elderly hospitalized patients with BPH(P<0.05).Conclusion The abnormal level of blood glucose and blood lipid metabolism in middle-aged and elderly hospitalized patients with benign prostatic hyperplasia has a positive correlation with the severity of the disease.Therefore,the disease status of patients can be evaluated by detecting the blood glucose and blood lipid levels of patients,so as to provide effective guidance basis for clinical treatment.
作者 扈晓晴 王军喜 刘洁园 HU Xiaoqing;WANG Junxi;LIU Jieyuan(Department of Clinical Laboratory,Nanxiong People′s Hospital,Nanxiong Guangdong 512400,China)
出处 《中国卫生标准管理》 2025年第2期98-101,共4页 China Health Standard Management
基金 韶关市卫生健康科研项目(Y23150)。
关键词 中老年患者 良性前列腺增生 血糖 血脂 代谢异常 病情严重程度 middle-aged and elderly patients benign prostatic hyperplasia blood sugar blood lipid metabolic abnormality severity of illness
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