摘要
近年来,中药多糖因较低的毒副作用,多样的药理活性以及广阔的应用前景,成为天然药物开发及应用研究的热点。对近5年的中药多糖研究进行了追踪,汇总整理了中药多糖发挥的抗肿瘤、免疫调节、糖脂代谢、肠道菌群、抗氧化及其他药理活性,并对影响中药多糖药理活性的因素进行了剖析。分析了当前中药多糖研究中存在的局限性,并对未来中药多糖的应用前景进行展望,旨在提高中药材的利用率,明确中药多糖的药理活性,从而加速中药多糖的成果转化及应用推广。
In recent years,polysaccharides in traditional Chinese medicine have become a hot spot in the development and application of natural medicines due to their low toxicity and side effects,diverse pharmacological activities,and broad application prospects.We tracked the research on polysaccharides in traditional Chinese medicine in recent years,summarized the anti-tumor,immunomodulatory,glucose and lipid metabolism,intestinal microbiota,antioxidant,and other pharmacological activities of traditional Chinese medicine polysaccharides,and analyzed the factors affecting the pharmacological activities of traditional Chinese medicine polysaccharides.The limitations of the current research on polysaccharides in traditional Chinese medicine was analyzed and the future application prospects of polysaccharides in traditional Chinese medicine was presented,to achieve three aims:first,to improve the utilization rate of traditional Chinese medicines,second,to clarify the pharmacological activity of traditional Chinese medicine polysaccharides,and third,to accelerate the transformation and application of traditional Chinese medicine polysaccharides.
作者
吕嘉璐
霍燕菊
张翼
LV Jia-lu;HUO Yan-ju;ZHANG Yi(Key Laboratory of Basic and Application Research of Beiyao,Heilongjiang University of Chinese Medicine,Harbin 150036,China;First School of Clinical Medicine,Heilongjiang University of Chinese Medicine,Harbin 150036,China)
出处
《化学试剂》
CAS
2025年第1期1-8,共8页
Chemical Reagents
关键词
中药多糖
药理活性
抗肿瘤
免疫调节
肠道代谢稳态调节
作用机制
traditional Chinese medicine polysaccharide
pharmacological activity
anti-tumor
immune regulation
regulation of intestinal metabolic homeostasis
mechanism
