摘要
四环素类抗菌药物对包括肺炎支原体、衣原体在内的多种病原体有较强的抗菌作用,在儿科临床的应用逐渐增多。由于儿童不同于成人的生理特点,亟需一个专门针对儿童四环素类抗菌药物临床应用的指导文件。该共识从四环素类药物的药学特性、作用机制、抗菌活性、耐药现状和耐药机制在儿童感染性疾病中的作用、不良反应及超说明书用药等方面,对该类药物在儿科临床的应用给出了全面建议,以指导临床合理使用。
Tetracycline antibiotics have strong antibacterial effect on a variety of pathogens including mycoplasma pneumoniae and chlamydia,and their application in children is gradually increasing.Due to the different physiological characteristics of children from adults,there is an urgent need for a special guidance document for the clinical use of tetracycline antibiotics in children.The consensus gives comprehensive recommendations on the clinical application of tetracycline drugs in pediatrics from the aspects of pharmaceutical characteristics,mechanism of action,antibacterial activity,status and mechanism of drug resist ance,effects in children with infectious diseases,adverse reactions and off-label drug use,so as to guide clinical rational use.
出处
《中国实用儿科杂志》
CSCD
北大核心
2024年第9期641-651,共11页
Chinese Journal of Practical Pediatrics
关键词
抗菌药物
四环素类
共识
儿童
antimicrobial drugs
tetracycline
consensus
child
