摘要
猪伪狂犬病(Porcine pseudorabies,PR)是由猪伪狂犬病病毒(Pseudorabies virus,PRV)引起的一种猪的急性传染病,疫苗免疫是有效预防该病的主要措施。2011年以来由于PRV变异毒株的出现,原有商品化疫苗对PRV变异毒株的免疫保护效果下降,致使PR在我国再度流行,研发可有效预防PRV变异毒株的猪伪狂犬病疫苗成为新的研究热点。论文从PRV疫苗的种类分析比较不同时期、不同方法构建的PRV疫苗优缺点,并阐述不同种类的PRV疫苗的特性及免疫保护效果等研究现状,以期为相关领域研究人员提供参考。
Porcine pseudorabies(PR)is an acute infectious disease of pigs which caused by porcine pseudorabies virus(PRV).Vaccine immunization is the main measure to effectively prevent the disease.Since 2011,the immune protection effect of original commercial vaccine decreased because of the emergence of PRV mutant strains,resulting in the re-prevalence of PR in China.The research and development of porcine pseudorabies vaccine which can effectively prevent PRV mutant strains has become a new research hotspot.This paper analyzed and compared the advantages and disadvantages of PRV vaccines which were constructed in different periods and by different methods,and expounded the research status of the characteristics and immune protection effects of different types of PRV vaccines,so as to provide references for researchers in related fields.
作者
李雅雯
张莉
丁向彬
鄢明华
LI Ya-wen;ZHANG Li;DING Xiang-bin;YAN Ming-hua(College of Animal Science and Veterinary Medicine,Tianjin Agricultural University,Tianjin,300384,China;Animal Husbandry and Veterinary Research Institute,Tianjin Academy of Agricultural Sciences,Tianjin,300381,China;Tianjin Observation and Experiment Site of National Animal Health,Tianjin,300381,China;Tianjin Engineering Research Center for Livestock and Poultry Health Breeding,Tianjin,300381,China)
出处
《动物医学进展》
北大核心
2024年第3期125-128,共4页
Progress In Veterinary Medicine
基金
天津市科技支撑重点项目(18YFZCNC01110)
天津市农业科学院院级青年创新基金项目(201905)
天津市重大推广项目(ITTPRS2021003)。
关键词
猪
伪狂犬病
疫苗
swine
Pseudorabies
vaccine
research progress
