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胆红素与心血管疾病 被引量:19

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摘要 胆红素是一种生理性抗氧化剂 ,其活性受胆红素氧化酶 (HO)的影响。HO有三种异构体 ,HO 1是诱导式 ,HO 2和HO 3是构造式 ,在细胞抗氧化防御机理中HO 1有重要作用。胆红素的抗氧化性质是使脂链断裂 ,阻止低密度脂蛋白的氧化 ,因此 ,血清高浓度胆红素可以减少动脉粥样硬化形成的危险性 ,而低浓度则可增加其发病率。
出处 《国外医学(临床生物化学与检验学分册)》 2002年第6期329-330,共2页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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