摘要
目的观察超声引导下微波消融(MWA)治疗侵犯被膜的甲状腺乳头状癌(PTC)的有效性和安全性。方法回顾性分析72例接受超声引导下MWA治疗的合并被膜侵犯的单发PTC患者,观察疗效及并发症;术后随访观察病灶大小,评估疾病进展情况。结果对72个病灶均一次性完全消融,技术成功率100%。2例(2/72,2.78%)出现声音嘶哑,分别于术后4、6个月自行好转。随访9~36个月,于6、9、12、18、24、30及36个月分别有2、13、19、6、2、6和2个病灶消失,消融后36个月病灶消失率69.44%(50/72);期间未见局部复发及远处转移,出现新发病灶、颈部淋巴结转移各2例。结论超声引导下MWA治疗侵犯被膜的PTC有效且安全。
Objective To observe the efficacy and safety of ultrasound-guided microwave ablation(MWA)for papillary thyroid carcinoma(PTC)with capsular invasion.Methods Data of 72 single PTC patients with thyroid capsular invasion underwent ultrasound-guided MWA were retrospectively analyzed.The therapeutic effect and complications were observed.Following-up was performed to observe the lesion size and evaluate disease progression.Results All 72 lesions were completely ablated at one time,and the technical success rate was 100%.Abnormal pronunciation occurred in 2 cases(2/72,2.78%)after MWA,and then recovered spontaneously 4—6 months later.During 9—36 months'following-up,2,13,19,6,2,6,2 and 2 lesions disappeared at 6,9,12,18,24,30 and 36 months,respectively,and the lesion disappearance rate 36 months after MWA was 69.44%(50/72).No local recurrence nor distant metastasis,while 2 cases of new lesions cervical lymph node metastases occurred each in 2 cases during the following-up period.Conclusion Ultrasound-guided MWA was minimally invasive,safe and effective for treating PTC with capsular invasion.
作者
伍洁
魏莹
赵朕龙
彭丽丽
李妍
卢乃聪
于明安
WU Jie;WEI Ying;ZHAO Zhenlong;PENG Lili;LI Yan;LU Naicong;YU Ming'an(Department of Interventional Medicine,China-Japan Friendship Hospital,Beijing 100029,China)
出处
《中国介入影像与治疗学》
北大核心
2023年第2期70-73,共4页
Chinese Journal of Interventional Imaging and Therapy
基金
国家自然科学基金项目(62176268)
首都临床特色应用研究项目(Z18l100001718135)
中央高水平医院临床科研业务费(2022-NHLHCRF-PY-07)。
关键词
甲状腺癌
乳头状
超声检查
消融技术
甲状腺被膜
thyroid cancer,papillary
ultrasonography
ablation techniques
thyroid capsule