摘要
目的探讨胃癌患者术后早期肠内营养不耐受的发生情况及其相关影响因素。方法回顾性选取90例2019年1月—2020年12月于我院行胃癌根治术并于术后行早期肠内营养的胃癌患者作为研究对象,根据患者行早期肠内营养后是否出现恶心、呕吐、腹胀、腹痛、腹泻等症状将其分为早期肠内营养耐受组(n=30)、早期肠内营养不耐受组(n=60)。比较两组一般资料,并采用多因素Logistic回归分析法分析胃癌患者术后早期肠内营养不耐受的危险因素。结果90例胃癌患者术后发生早期肠内营养不耐受60例,占比为66.67%。多因素Logistic回归分析结果显示,术后第1 d下床活动时间≤4 h、未使用营养泵为胃癌患者术后早期肠内营养不耐受的独立危险因素(OR=2.998;4.586,P<0.05)。结论胃癌患者术后早期肠内营养不耐受的危险因素为患者术后第1 d下床活动时间≤4 h、未使用营养泵,临床可据此给予患者针对性干预措施,以预防胃癌患者术后早期肠内营养不耐受情况的发生。
Objective To investigate the incidence of early enteral nutrition intolerance and related influencing factors in postoperative gastric cancer patients.Methods 90 gastric cancer patients who underwent radical gastric cancer surgery and received early enteral nutrition thereafter in our hospital were retrospectively enrolled from January 2019 to December 2020.Patients were divided into early enteral nutrition tolerance group(n=30)and intolerance group(n=60)according to whether they developed nausea,vomiting,abdominal distension,abdominal pain,diarrhea and other symptoms after early enteral nutrition.The general characteristics of the two groups were compared and the risk factors of early enteral nutrition intolerance in postoperative gastric cancer patients were analyzed using multivariate Logistic regression.Results 60(66.67%)of the 90 postoperative gastric cancer patients experienced early enteral nutrition intolerance.Multivariate Logistic regression analysis showed that≤4 hours of out-of-bed activity on the first postoperative day and nonuse of nutrition pump were independent risk factors for early enteral nutrition intolerance in these patients(OR=2.998;4.586,P<0.05).Conclusions The risk factors of early enteral nutrition intolerance in postoperative gastric cancer patients were≤4 hours of out-of-bed activity on the first postoperative day and nonuse of nutrition pump.Corresponding clinical interventions could be implemented to prevent the occurrence of early enteral nutrition intolerance in postoperative gastric cancer patients.
作者
杜雨家
史业东
孙小杰
Du Yujia;Shi Yedong;Sun Xiaojie(Department of Traditional Chinese medicine,Shengjing Hospital Affiliated to China Medical University,Shenyang 110000,China)
出处
《中华临床营养杂志》
CAS
CSCD
2021年第6期373-377,共5页
Chinese Journal of Clinical Nutrition
关键词
胃癌
胃癌根治术
早期肠内营养
不耐受
影响因素
Gastric cancer
Radical gastric cancer surgery
Early enteral nutrition
Intolerance
Influencing factors
