摘要
目的:分析原发性高血压及2型糖尿病患者血清同型半胱氨酸(Hcy)水平变化的临床意义。方法:选取2018年11月至2020年11月期间在高境镇社区卫生服务中心全科病房住院治疗的230例患者作为研究对象。将病情为原发性高血压合并2型糖尿病的50例患者作为A组,将病情为原发性高血压的60例患者作为B组,将病情为2型糖尿病的60例患者作为C组,将无内科系统慢性病的60例患者作为D组。对四组患者均进行血压、空腹血糖检测、血清糖化血红蛋白和血清Hcy检测。然后,对四组患者的检测结果进行分析研究,从中找出其血压的水平和血糖的水平与其血清Hcy水平的相关性。结果:A组患者血清Hcy的水平高于B组患者、C组患者和D组患者,B组患者和C组患者血清Hcy的水平均高于D组患者,P<0.05。结论:原发性高血压及2型糖尿病患者血清Hcy水平的变化可影响其血压和血糖的水平。
Objective:To analyze the clinical significance of serum homocysteine(Hcy)levels in patients with essential hypertension and type 2 diabetes mellitus.Methods:From November 2018 to November 2020,230 patients hospitalized in the general ward of Gaojing Town Community Health Service Center were selected as the research objects.Fifty patients with essential hypertension combined with type 2 diabetes were included in group A,60 patients with essential hypertension were included in group B,60 patients with type 2 diabetes were included in group C,and 60 patients without chronic medical diseases were included in group D.Blood pressure,fasting glucose,serum glycosylated hemoglobin and serum Hcy were measured in all four groups.Then,the test results of the four groups of patients were analyzed and studied to find out the correlation between their blood pressure and blood glucose levels and their serum Hcy levels.Results:The serum Hcy level of group A was higher than that of group B,GROUP C and group D,and the serum Hcy level of group B and GROUP C was higher than that of group D,P<0.05.Conclusion:Changes of serum Hcy level can affect blood pressure and blood glucose levels in patients with essential hypertension and type 2 diabetes.
作者
陈云峰
朱晨菲
CHEN Yunfeng;ZHU Chenfei(Gaojing Town Community Health Service Center,Baoshan District,Shanghai 200435,China)
