摘要
目的探究高尿酸血症与非酒精性脂肪性肝病(NAFLD)的相关性。方法 2014年7月至2018年6月安钢总医院收治的175例NAFLD患者作为观察组,另择同期健康体检的175例非NAFLD者作为对照组。比较两组高尿酸血症检出率、高尿酸血症不同水平与NAFLD的发病关系。结果观察组高尿酸血症检出率高于对照组(25.14%vs. 5.71%),差异有统计学意义(P<0.05)。按观察组高尿酸血症不同尿酸水平分位,第一分位至第四分位的NAFLD发病率分别为4.55%、13.64%、29.55%及52.27%。影响NAFLD的Logistic回归模型分析显示,高尿酸血症是NAFLD发病的独立危险因素[OR=1.624 (95%CI:1.151~1.705), P=0.001]。结论高尿酸血症是NAFLD发生的危险因素,且随着尿酸水平增高,NAFLD发病率呈增高趋势。
【Objective】 To explore the correlation between hyperuricemia and nonalcoholic fatty liver disease(NAFLD).【Methods】 The clinical data of 175 patients with NAFLD admitted to our hospital from July 2014 to June 2018 were retrospectively analyzed. They were classified as observation group, and 175 non-NAFLD patients who received health check-up at the same time were taken as control group. The detection rate of hyperuricemia and the relationship between different levels of hyperuricemia and the incidence of NAFLD were compared between the two groups.【Results】The detection rate of hyperuricemia in the observation group was 25.14%, higher than that in the control group(5.71%)(P<0.05). According to the different levels of uric acid in the observation group, the incidence of NAFLD in the first to fourth ranks was 4.55%, 13.64%, 29.55% and 52.27%,respectively. Logistic retrospective analysis of risk factors for NAFLD showed that hyperuricemia was an independent risk factor for NAFLD [ ■=1.624(95% CI: 1.151~1.705), P=0.001].【Conclusion】 Hyperuricemia is an independent risk of NAFLD, and the incidence of NAFLD tends to increase with the increase of uric acid level.
作者
李丽淑
LI Lishu(Department of Endocrine,Angang General Hospital,Anyang,Henan 455000,China)
出处
《中国医学工程》
2020年第8期33-34,共2页
China Medical Engineering
