摘要
胃肠道是HIV感染的主要部位,肠道菌群及其代谢产物可对肠道的理化性质、营养状态及免疫功能产生影响,改善艾滋病患者的肠道菌群状态,可提高患者的免疫功能,抑制HIV病毒对机体造成的损伤。辣木复合肠内营养可改善艾滋病患者的肠道微生态,有效提高患者的营养状况,但存在与抗病毒药物及大蒜、贯叶金丝桃等草药相互作用的可能。微生态制剂对艾滋病患者肠道菌群的调节作用较弱,但可在一定程度上提高患者的免疫功能。粪便菌群移植对艾滋病患者的肠道菌群多样性改变不明显,且远期并发症尚待明确,但可在一定程度上提高患者免疫力。微生态制剂的保存、饮食调节肠道菌群状态、艾滋病患者粪便菌群移植后的护理等方面尚待研究。
Gastrointestinal tract is the main site of human immunodeficiency virus(HIV)infection.Intestinal flora and its metabolites can affect the physicochemical properties,nutritional status and immune function of the intestinal tract.Improving the state of intestinal flora of AIDS patients can improve the immune function of patients and suppress the damage caused by HIV virus to the body.Moringa oleifera combined enteral nutrition can improve the intestinal microecology of AIDS patients and effectively improve the nutritional status of the patients,but there is the possibility of interaction with antiviral drugs,garlic,hypericum perforatum and other herbs.The microbial ecological agents have a weak regulation effect on the intestinal flora of AIDS patients,but it can improve the immune function of patients to a certain extent.Fecal microbiota transplantation does not significantly change the diversity of intestinal flora in AIDS patients,and the long-term complications are still to be clarified,but it can improve the immunity of patients to some extent.The preservation of microbial ecological agents,dietary regulation of intestinal flora and nursing after fecal microbiota transplantation in AIDS patients are still to be studied.
作者
卢凤玲
刘宇
段红梅
杨开连
吴诗诗
欧梦仙
Lu Fengling;Liu Yu;Duan Hongmei;Yang Kailian;Wu Shishi;Ou Mengxian(School of Nursing,Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《中华现代护理杂志》
2020年第20期2694-2697,共4页
Chinese Journal of Modern Nursing
关键词
综述
艾滋病
肠道微生态
辣木
微生态制剂
粪便菌群移植
Review
AIDS
Intestinal microecology
Moringa oleifera
Microbial ecological agents
Fecal microbiota transplantation
