摘要
胰岛素抵抗(IR)是指胰岛素促进葡萄糖摄取和利用的效率下降,是母猪采食量下降的重要因素。母猪IR常与妊娠期过肥、氧化应激和炎症反应密切相关,妊娠过程中肠道菌群结构的变化是导致母猪IR的重要原因。作为益生元物质,功能性寡糖可通过调节肠道菌群稳态、提高机体抗氧化和免疫能力,从而改善母猪IR。本文综述了功能性寡糖在调控母猪IR中的作用及其机制,为益生元物质在母猪生产中的应用提供理论依据。
Insulin resistance(IR) refers to the decrease in the efficiency of insulin-induced glucose uptake and utilization,and is an important factor in the decline in sowfeed intake. IR in sowis often associated with hypertrophy,oxidative stress and inflammatory response during gestation. Changes in gut microbiota during pregnancy are important causes of sow’s IR. As a prebiotic substance,functional oligosaccharides can improve sow’s IR by regulating the homeostasis of gut microbiota and improving the body ’s antioxidant and immune capabilities. This article reviews the role of functional oligosaccharides in regulating IR in sows and its mechanism,and provides a theoretical basis for the application of prebiotics in sowproduction.
作者
谷雪玲
陈将
李浩
范志勇
GU Xueling;CHEN Jiang;LI Hao;FAN Zhiyong(Hunan Agricultural University,College of Animal Science and Technology,Changsha 410128,China;Hunan Co⁃Innovation Center of Animal Production Safety,Changsha 410128,China)
出处
《动物营养学报》
CAS
CSCD
北大核心
2019年第12期5422-5430,共9页
CHINESE JOURNAL OF ANIMAL NUTRITION
基金
国家重点研发计划(2017YFD0500506,2016YFD0501209)
湖南农业大学“双一流”建设项目(SYL201802015,SYL201802009)
关键词
功能性寡糖
母猪
胰岛素抵抗
机制
functional oligosaccharide
sows
insulin resistance
mechanism
