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铅对儿童骨代谢的影响机制 被引量:18

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摘要 铅作为有毒重金属对处于生长发育旺盛时期的儿童有不容忽视的影响,本文系统复习了多年来的国内外资料,从铅对钙磷代谢及成骨细胞的直接和间接影响等方面阐明铅对儿童骨代谢的影响机制,指出铅中毒可能是引起小儿骨代谢障碍的又一原因,同时提出维生素D受体的基因多态性可能通过影响铅-钙的相互作用而改变体内铅的毒物代谢和毒物效应动力学。
出处 《国外医学(儿科学分册)》 2002年第6期289-291,共3页 Foreign Medical Sciences(Section of Pediatrics)
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