摘要
目的探究阿替普酶静脉溶栓在治疗脑梗死方面的疗效。方法选择2013年1月至2018年1月本院收治的83例脑梗死患者作为本次的研究对象,按照数字随机法将其分为观察组与对照组。观察组42例,对照组41例。对照组选用阿司匹林配合波立维治疗,观察组采用阿替普酶溶栓治疗。分别统计治疗后两组患者的NIHSS评分,来判断不同治疗方式的效果。结果研究结果表明,观察组和对照组在溶栓前的NIHSS评分上比较差异无统计学意义,但是在溶栓后1 d与溶栓后7 d,观察组的NIHSS评分明显优于对照组;此外在出血情况上,观察组出现了1例牙龈出血、1例消化道出血、2例血尿,发生率为9.5%,而对照组出现了3例牙龈出血、2例消化道出血、2例颅内出血与2例血尿,发生率为22.0%。两组患者在各项数据对比差异具有统计学意义(P<0.05)。结论在治疗时间窗内,阿替普酶溶栓治疗的方式治疗脑梗死的疗效显著,可以作为今后临床上主要的治疗模式,具有推广价值。
Objective To explore the efficacy of intravenous thrombolysis with opiopout in the treatment of cerebral infarction.Methods 83 patients with cerebral infarction treated in our hospital from January 2013 to January 2018 were selected as the subjects,and they were divided into the observation group and the control group according to the digital random method.There were 42 cases in the observation group and 41 in the control group.The control group was treated with aspirin plus boliwei,while the observation group was treated with intravenous thrombolytic therapy.The NIHSS scores of the two groups after treatment were respectively used to judge the effect of different treatments.Results The results showed that there was no significant difference in the NIHSS score between the observation group and the control group before thrombolysis,but the NIHSS score of the observation group was significantly better than that of the control group after thrombolytic 1 d and 7 d after thrombolysis;in addition, there were 1 cases of gingival bleeding,1 cases of digestive tract bleeding and 2 cases of hematuria in the observation group.The incidence rate was 9.5.In the control group,there were 3 cases of gingival bleeding,2 cases of gastrointestinal bleeding,2 cases of intracranial hemorrhage and 2 cases of hematuria,the incidence was 22%.The two groups of patients had significant differences in the data comparison,and the results of the study data were statistically significant (P<0.05).Conclusion In the treatment time window,the method of thrombolytic therapy with opiopout is significant in the treatment of cerebral infarction,and it can be used as the main treatment model in the future,and it is of great value for popularization.
作者
杨刚
赵叶清
Yang Gang;Zhao Yeqing(Department of Neurology,Fengcheng People's Hospital,Fengcheng,Jiangxi,331100,China)
出处
《当代医学》
2019年第15期67-69,共3页
Contemporary Medicine
关键词
阿替普酶
静脉溶栓
脑梗死
疗效分析
Aciopysin
Intravenous thrombolysis
Cerebralinfarction
Curative effect analysis
