摘要
目的:探讨小儿肺炎支原体感染的诊断方法及治疗效果。方法:收治支原体肺炎患儿80例,随机分成观察组和对照组,各40例。对照组3岁以下口服阿奇霉素10 mg/kg,1次/d,服3 d停4 d,2周1个疗程;3岁以上给予阿奇霉素注射液10 mg/kg+200 mL 5%葡萄糖注射液静脉滴注,1次/d,连续治疗6 d,改为口服,2周1个疗程。观察组在对照组的基础上联合应用氨溴索注射液7.5 mg+50 mL 5%葡萄糖注射液静脉滴注,2次/d,连续治疗7 d。结果:流行病学特点、临床症状、实验室检查和胸片检查是诊断小儿支原体肺炎的重要措施依据。经过治疗,观察组患者的退热时间、咳喘消失时间、肺部啰音消失时间、肺部炎症消失时间明显短于对照组(P<0.05),观察组患者用力肺活量(FVC)、第1秒最大呼气量(FEV_1)、最大呼气流速(PEF)、用力呼气25%流速(MEF25)、用力呼气50%流速(MEF50)均明显高于对照组(P<0.05),观察组总有效率明显高于对照组(P<0.05)。结论:流行病学特点、临床症状、实验室检查和胸片检查是诊断小儿支原体肺炎的重要措施依据。阿奇霉素联合氨溴索治疗小儿支原体肺炎效果显著。
Objective:To explore the diagnosis method and treatment effect of mycoplasma pneumoniae infection in children.Methods:80children with mycoplasma pneumoniae infection were selected.They were randomly divided into the observationgroup and the control group with40cases in each.In the control group,the children under3years old were given oral azithromycin10mg/kg,1time one day,eating3days and stopped4days,2weeks of1course;the children above3years old were givenazithromycin injection10mg/kg and200mL5%glucose injection intravenous infusion,1time one day,continuous treatment for6days,changed to oral,2weeks of1course.On the basis of the control group,the observation group was given ambroxolhydrochloride injection7.5mg and50mL5%glucose injection intravenous infusion,2times one day,continuous treatment for7days.Results:Epidemiological characteristics,clinical symptoms,laboratory tests and chest X-ray examination were importantmeasures for the diagnosis of mycoplasma pneumoniae in children.After treatment,the antifebrile time,cough disappeared time,pulmonary rales disappeared time and pulmonary inflammation disappeared time of the observation group were significantlyshorter than those of the control group(P<0.05).The forced vital capacity(FVC),first second maximal expiratory volume(FEV1),maximal expiratory flow rate(PEF),forced expiratory25%flow rate(MEF25),forced expiratory50%flow rate(MEF50)of theobservation group were significantly higher than those of the control group(P<0.05).The total effective rate of the observationgroup was significantly higher than that of the control group(P<0.05).Conclusion:Epidemiological characteristics,clinicalsymptoms,laboratory tests and chest X-ray examination are important measures for the diagnosis of mycoplasma pneumoniae inchildren.Azithromycin combined with ambroxol in the treatment of mycoplasma pneumonia in children has a significant effect.
作者
王芳
Wang Fang(Department of Paediatrics,Ezhou City Maternal and Child Health Hospital of Hubei Province 436000)
出处
《中国社区医师》
2017年第12期49-50,共2页
Chinese Community Doctors
关键词
阿奇霉素
小儿
支原体肺炎
氨溴索
Azithromycin
Children
Mycoplasma pneumoniae
Ambroxol
