摘要
目的了解肺炎支原体（mycoplasma pneumoniae,MP）感染与儿童呼吸道疾病之间的关系。方法用颗粒凝集法检测2006年7月至2007年6月我院儿科住院病房464例呼吸道感染患儿的MP抗体效价,比较不同月份、不同年龄及不同临床表现的患儿的MP-IgM阳性率。结果464例患儿中211例MP-IgM为阳性,占住院总人数的45%,一年中12月、1月是MP感染的高峰季节,其阳性率分别为60%和58.3%（χ^2=20.03,P〈0.05）;随着年龄增长,MP感染阳性率增高,10～14岁儿童MP阳性率高达75%,而1岁以下婴儿MP阳性率仅为13.3%（χ^2=72.6,P〈0.001）;支气管哮喘患儿中MP-IgM阳性率最高,为64.5%（χ^2=24.5,P〈0.001）。结论呼吸道感染患儿肺炎支原体抗体阳性率高,该病原体是目前儿科感染的常见病原体。
Objective To study the relationship between mycoplasma pneumoniae （MP） and respiratory tract diseases in children. Methods Four hundred and sixty four patients from July 2006 to June 2007 who had been serologically tested for MP-IgM by using particle diameter agglutination were enrolled. The positive rate of MP-IgM in patients in different months, with different age and different clinical manifestations were compared. Results MP-IgM antibody titre of two hundred and eleven patients were positive, the positive rate was 45%. December and January were peak months of MP infection while the positive rate were 60% and 58.3 respectively （χ^2 = 20.03, P 〈 0.05）. Along with age growth, the positive rate of MP infection was increased. It reached up to 75% in 10 to 14 years old children, while it was only 13.3% in children below one years old（χ^2 = 72.6, P 〈 0. 001 ）. The highest positive rate of MP-IgM was in the patients with bronchial asthma, which was 64.5 % （χ^2 = 24.5, P 〈 0.001 ）. Conclusion The positive rate of MP-IgM antibody titre is high in patients with respiratory tract diseases. MP is a common pathogen in pediatrics.
出处
《同济大学学报（医学版）》
CAS
2008年第3期118-120,共3页
Journal of Tongji University(Medical Science)
关键词
儿童
肺炎支原体
呼吸系统
children
mycoplasma pneumoniae
respicrtory ststem
