摘要
目的:对盐酸氨基葡萄糖胶囊辅助治疗类风湿关节炎致膝软骨损伤的可行性进行分析。方法:选取2014年01月-2016年02月在我院因类风湿关节炎致膝软骨损伤的80例患者为治疗研究对象,将这80例患者随机分为对照组和研究组,对照组40例予以常规治疗,研究组40例则在常规治疗的基础上加盐酸氨基葡萄糖胶囊进行辅助治疗,在治疗12周后对患者软骨损伤指标进行对比和分析,用DAS28评分用药疗效进行评估同时记录不良反应反生情况。结果:与对照组相比,研究组在治疗12周后的血清关节软骨损伤指标显著降低(P<0.05)、DAS28具有明显差异(P<0.05)。结论:在常规药物的治疗下加以盐酸葡萄糖胶囊治疗方法有效可行。
Objcetive: To analyze the feasibility of glucosamine hydrochloride capsules auxiliary treatment for rheumatoid arthritis in knee cartilage injury. Methods: 80 rheumatoid arthritis (RA) patients for the treatment of knee cartilage damage from February 2014 to January 2016 in our hospital,were randomly divided into control group and research group, 40 cases in control group conduct conventional treatment, another 40 cases in research group got glucosamine hydrochloride capsule on the basis of routine treatment. 12 weeks after treatment, cartilage damage index, adverse reactions was compared by DAS28 score. Results: 12 weeks after treatment, serum levels of articular cartilage damage index of the research group was lower comparedwith the control group, (P<0.05). DAS28 has obvious difference (P<0.05). Conclusion: Combined with the routine drug treatment, glucose hydrochloride capsule treatment method is effective and feasible.
作者
舒伟明
SHU Wei-ming(People's Hospital of Jiangxi Zhangshu City, Department of orthopedics, Zhangshu Jiangxi 331200, China)
出处
《药品评价》
CAS
2016年第24期37-39,共3页
Drug Evaluation
