摘要
目的观察盐酸氨基葡糖糖胶囊(奥泰灵)治疗类风湿关节炎致膝软骨损伤患者的临床效果。方法将94例类风湿关节炎而导致膝软骨受到损伤的患者随机分成研究组与对照组,每组47例。对照组患者给予常规抗风湿治疗措施,研究组在此基础上给予盐酸氨基葡糖糖胶囊治疗。比较两组的治疗效果。结果治疗后两组患者DAS28评分、不良反应发生情况比较差异不显著(P>0.05),但治疗后研究组Lequesne指数明显低于对照组(P<0.05),NOYES软骨分级情况明显优于对照组(P<0.05)。结论选择盐酸氨基葡糖糖胶囊配合抵抗风湿的药物治疗类风湿关节炎致膝软骨损伤患者,疗效满意,值得在临床中推广及应用。
Objective To observe the clinical effects of glucosamine hydrochloride capsules（Aotailing） in treatment of patients with knee cartilage damage induced by rheumatoid arthritis. Methods 94 patients with knee cartilage damage induced by rheumatoid arthritis were selected and randomly divided into study group and control group, with 47 cases in each group. The control group was given conventional anti-rheumatic therapy, and the study group was given glucosamine hydrochloride capsules on this basis. The clinical effects of two groups were compared. Results After treatment, the DAS28 scores and adverse reactions of two groups had no statistical difference（P0.05）, but the Lequesne indices of study group were significantly lower than those of control group（P〈0.05）, and the NOYES cartilage classification of study group was significantly better than that of control group（P〈0.05）. Conclusions Glucosamine hydrochloride capsules combined with conventional anti-rheumatic drug in treatment of patients with knee cartilage damage induced by rheumatoid arthritis has satisfactory effect, which is worthy of promotion and application in clinic.
出处
《临床医学工程》
2016年第2期201-202,共2页
Clinical Medicine & Engineering
