摘要
目的 探讨胆固醇结石的预防。方法 采用豚鼠为实验对象 ,随机分为三组 ,设置了空白组、对照组、预防组。结果 药物预防组较对照组成石率显著降低 (P <0 0 5 ) ,药物预防组胆汁中胆固醇含量较对照组显著降低 (P <0 0 5 ) ,胆汁酸含量较对照组显著升高 (P <0 0 5 )。结论 绞股蓝能改善肝细胞功能 ,降低胆汁中胆固醇含量 ,提高胆汁酸含量 ,达到预防胆固醇结石形成的目的。
Objective To study the prevention of cholesterol gallstone. Methods Guinea pigs were randomized into the blank group, control group and preventive group. Results The incidence of gallstone and cholesterol quantity in the bile were significantly lower but quantity of cholic acid markedly higher in the preventive group than in the control (P<0.05). Conclusions Gynostemma-pentaphyllum can improve the liver function, reduce the quantity of biliary cholesterol and increase the quantity of chlic acid, which contributes to prevention of cholesterol gallstone formation.
出处
《中华肝胆外科杂志》
CAS
CSCD
2002年第10期609-610,共2页
Chinese Journal of Hepatobiliary Surgery
关键词
绞股蓝
预防
豚鼠
胆囊
胆固醇结合
胆结石
Cholelithiasis
Gyonstemma-pentaphyllum
Prevention
Cholic acid