摘要
目的进一步研究血浆脂联素水平、胰岛素抵抗在胆囊胆固醇结石形成的作用。方法应用酶联免疫分析法(ELISA)测定50例胆囊胆固醇结石患者(实验组)与30例对照组其血浆脂联素、空腹胰岛素(FINS)、空腹血糖水平,并计算出体重指数(BMI)、胰岛素抵抗指数(HOMA-IR)、胰岛素敏感指数(ISI)。结果实验组血清中FINS、HOMA-IR、BMI较对照组高,而脂联素、ISI低于对照组,差异有统计学意义(P<0.05)。结论脂联素、胰岛素抵抗与胆囊胆固醇结石的形成关系密切。
Objective To further study the role of adiponectin and insulin resistance in the process of formation of gallbladder stone.Methods Fifty patients with cholesterol gallstone patients and thirty cases of control group were chosen to detect plasma adiponectin,fasting insulin（FINS） and fasting plasma glucose levels（FPG） using enzyme-linked immunosorbentassay.Meanwhile,BMI、HOMA-IR、ISI were assayed.Results The blood Leptin Insulin（FINS）,HOMA-IR,BMI in patients with gallstone were significantly higher than those of controls.Against ISI,adiponectin level were lower than those of control（P0.05）.Conclusion Adiponectin and insulin resistance may be involved in the formation of gallstones.
出处
《肝胆胰外科杂志》
CAS
2012年第2期96-98,共3页
Journal of Hepatopancreatobiliary Surgery
关键词
脂联素
胰岛素抵抗
胆结石
adiponectin
insulin resistance
gallstone
