摘要
对5组316例心脏病患者作信号平均心电图(SAECG)检查,其中266例(84%)作 Holter 动态心电图。结果显示:心绞痛、心肌梗塞、心肌炎、心肌病和原因不明的心律失常组晚电位(VLP)阳性率分别为6.1&、25.0%、25.7%、14.3%和5.5%。V-LP 阳性组复杂性室性心律失常比例显著高于阴性组(P<0.05),VLP 检出复杂性室性心律失常的特异度在80%以上,阳性预测值达70～80%。药物干预试验结果显示慢心律、利多卡因和中药黄芪治疗均不能使 VLP 消失,但黄芪治疗可显著缩短 VLP 时限(治前44.5±5.9ms,治后39.88±3.3 ms,P<0.01)。
The body surface signal-averaged electrocardiogram(SAECG)was recorded on 316 cardiac patients,84%(266 patients)of whom were also taken 24-hour Holter ECG.YLPs were detected positively in 6.1%,25%,25.7%,14.3%and 5.5% of patients with angina pectoris,myocardial infarc- tion,myocarditis,cardiomyopathy and arrhythmia of unknown origin respectively,and the patients with complex ventricular arrhythmia had more VLPs positive determination definitely(P<0.05). The specificity of VLPs in the prediction of complex ventricular arrhythmia was>80%,and the positive predictive accuracy was 70～80%.5,5 and 10 patients with VLFs were treated with Mexiletini Hydrochloridum,Lidocaini Hydrochloridum and Injection of Astragalus membranaceus respectively.As a result of treatment,the transfer of VLPs positive to negative was unsuccessful,but only the intervention of Astragalus membranaceus Injection made the duration of VLPs shortened significantly(39.8±3.3 ms versus 44.5±5.9 ms,P<0.01).
关键词
心室晚电位
黄芪
心电图
SAECG
signal-averaged electrocardiogram
ventricular late potentials
Astragalus membra-
