摘要
对42例急性脑损伤患者伤后48小时内脑脊液和血浆过氧化脂质(CSF-LPO和P-LPO)含量检测的结果表明,CSF-LOP和P-LPO含量显著高于对照组(P<0.001～0.005);脑损伤程度、颅内压与CSF-LPO和P-LPO皆呈密切相关(P<0.05～0.001);脑创伤时间、颅内血肿量与CSF-LPO呈密切相关(P<0.005～0.001).但与P-LPO不呈相关;死亡组的CSF-LPO含量显著高于生存组(P<0.001),但两组P-LPO间无显著差异;提示急性脑损伤患者伤后颅内膜脂质过氧化反应剧增,说叫CSF-LPO和P-LPO,尤其是CSF-LPO含量检测对判断脑损伤程度和评估预后有一定的参考价值。
Lipid peroxid levels in cerebrospinal fluid and in plasma among 42 cases of acute craniocerebral injuries within 48 hours after accident were measured. The results showed that the mean levels of CSF-LPO and P-LPO were significantly higher than those of the control group (P<0.005～0.001). CSF-LPO and P-LPO levels were closely related to the condion of craniocerebral injury, wheras CSF—LPO levels were closely related to the time of craniocerebral injury and the size of intracranlal hemotaoma. CSF-LPO level in mortality group was siginificantly higher than that in survival group (P<0.001).
出处
《中华创伤杂志》
CAS
CSCD
北大核心
1991年第1期1-4,共4页
Chinese Journal of Trauma
关键词
脑损伤
脑脊液
过氧化脂质
血浆
brain injury cerebrospinal fluid lipid peroxide
