摘要
目的评估基于学校的中国儿童与青少年意外伤害综合干预措施的效果,为今后学校意外伤害的干预提供参考依据。方法检索中国生物医学文献数据库、中国知网、万方数据库、中文科技期刊全文数据库,PubMed,EMBASE,CINAHL,SCOPUS,Psyc INFO,BIOSIS Previews数据库,收集由建库至2018年2月3日的中国基于学校儿童与青少年意外伤害综合干预措施相关文献,用相对危险度(RR)及其95%置信区间(95%CI)作为干预效果测量的指标,使用R 3.3.3软件进行分析,采用Meta回归和亚组分析探索异质性来源研究协变量对合并效应的影响。使用漏斗图与Egger加权线性回归法评估发表偏倚,采用敏感性分析判断结果的稳定性。结果最终有23篇随机对照试验纳入分析,被纳入研究的总样本量为52 387人;Meta分析结果显示,基于学校的意外伤害综合干预措施效果的合并效应量RR(95%CI)值为0.67(0.60～0.74)。Meta回归分析与亚组分析发现,对儿童和青少年研究对象的学段越高相应的RR值越小。敏感性分析显示结果较为稳定。结论中国基于学校的意外伤害综合干预措施能够有效预防儿童与青少年意外伤害的发生。
Objective To evaluate the effect of school-based unintentional injury prevention programs for children and adolescents in China and to provide evidence for future program. Methods Database CNKI, Wanfang Data, CQVIP, CBM, Pub Med,EMBASE, CINAHL, SCOPUS, Psyc INFO, BIOSIS Previews were searched from inception to Feb. 3 rd 2018, to collect studies about school-based unintentional injury prevention programs in China. Intervention effects were measured as relative risk（ RR） and their 95% confidence interval（ CI）. The Meta-analysis was performed by R 3.3.3 software. Meta-regression analyses and subgroup analysis were used to explore sources of heterogeneity. Funnel plots were used to examine the publication bias and asymmetry was tested by Egger＇s weighted regression. The stability of the results was assessed by performing the sensitivity analysis. Results Twenty-three RCT, involving a total of 52 387 participants, were included in the Meta-analysis, pooled RR（ 95%CI） was 0.67（ 0.60-0.74）. Meta regression analysis and subgroup analysis found that among children and adolescents the higher the grade was, the lower the RR became. The analysis of sensitivity showed that the results were quite stable. Conclusion School-based injury prevention programs is an effective measure to prevent unintentional injuries for children and adolescents in China.
作者
郝秀奇
代涛
HAO Xiuqi;DAI Tao(Peking Union Medical College,Beijing（100020）,China)
出处
《中国学校卫生》
CAS
北大核心
2018年第8期1206-1209,1212,共5页
Chinese Journal of School Health
关键词
干预性研究
青少年
儿童
因素分析
创伤和损伤
Intervent studies
Adolescent
Child
Factor analysis
Wounds and injuries
