摘要
目的探讨彩色多普勒超声检测糖尿病肾病(DN)早期肾脏声像改变的临床价值。方法收集该院2016年1月至2017年9月收治的早期糖尿病患者80例作为观察组,同时80例健康体检者作为对照组。采用彩色多普勒超声检测各组研究对象肾脏二维及肾实质叶间动脉血流参数,记录肾脏长径、肾实质厚度、肾窦厚度,并计算肾实质厚度/肾窦厚度比值、肾实质叶间动脉血流阻力指数(RI),并对各组各项参数进行比较。结果观察组患者肾脏长径、实质厚度、肾窦厚度、实质厚度/肾窦厚度比值均高于对照组,差异有统计学意义(P<0.05);观察组患者肾实质叶间动脉舒张期最低血流速度(Vmin)明显低于对照组,而RI高于对照组,差异有统计学意义(P<0.05),2组肾脏肾实质叶间动脉收缩期最大血流速度(Vmax)比较,差异无统计学意义(P>0.05)。结论彩色多普勒超声可以检测DN早期肾脏二维结构及肾实质叶间动脉血流动力学参数,可反映肾脏结构及肾实质叶间动脉血流灌注的改变,为临床治疗早期肾功能损伤提供重要诊断价值。
Objective To investigate the diagnostic significance of color Doppler ultrasonography for detecting the change of renal in early Diabetic Nephropathy patients. Methods The patients with Diabetic Nephropathy were chosen as observation group （ n =80） and the objects with physical examinations were chosen as control group （ n =80） from the Department of Ultrasonography of Central Hospital of Longgang in Shen Zhen City.All objects were given the detections of 2D gray-scale and color Doppler ultrasonography,and some indexes including renal length,renal parenchymal thickness,thickness of renal sinus and ratio of parenchymal thickness to sinus thickness,and hemodynamic parameters of segment of interlobular renal artery （IRA） at cortex-medulla junction were compared in 2 groups. Results The indexes of renal length,renal parenchymal thickness,thickness of renal sinus and ratio of parenchymal thickness to sinus thickness were all higher in observation group than those in control group （ P 〈0.05）.The minimum diastolic flow velocity （Vmin） was lower in observation group than that in control group （ P 〈0.05）,the resistance index （RI） in observation group was higher than that in control group （ P 〈 0.05）,but the value of Vmax has no statistical difference between two groups （ P 〉0.05）. Conclusion Color Doppler ultrasonography can be used for detecting 2D gray-scale change and hemodynamic parameters of diabetic renal arteries,which can reflect the changes in secondary renal perfusion and provide important evidence in diagnosis of early renal damage in patients with Diabetic patients.
作者
尤东华
贾保霞
刘滨月
YOU Donghua,JIA Baoxia,LIU Binyue △(Department of Ultrasound,Longgang Central Hospital of Shenzhen,Shenzhen,Guangdong 518116,China)
出处
《检验医学与临床》
CAS
2018年第17期2600-2601,2604,共3页
Laboratory Medicine and Clinic
关键词
糖尿病肾病
彩色多普勒超声
肾实质叶间动脉
diabetic nephropathy
color doppler ultrasonography
interlobular artery of renal parenchyma
