摘要
本研究分别观察了豚鼠在噪声暴露(105±2dBA,持续0.5h),γ射线照射(80Gy一次暴露)及γ射线照射后接着噪声暴露三种情况下豚鼠的听阈偏移。实验结果表明噪声暴露组豚鼠的听阈偏移在暴露后96h内恢复。γ射线照射组的最大阈移在照射后96h为9dB(4kHz)。γ射线照射后接着暴露于噪声的豚鼠的阈移大于噪声组和γ射线组阈移的总和。提示γ射线与噪声对豚鼠听阈产生了协同作用。
Guinea pigs were exposed to noise of 105 ± 2dBA SPL for 30 minutes, or 80Gy γ-irradiation, or γ-irradiation followed by noise exposure. At the frequencies of 250, 1 000 and 4 000 Hz, the hearing thresholds were measured using auditory cortex evoked response. In the noise exposure animals, mild threshold shift was found. The average threshold shift at 4 000 Hz in γ-irradiated animals 96 hours following exposure was 8.9dB. γ-irradiation followed by noise exposure resulted in a significant increase in threshold at all frequencies, exceeding the sum shift caused by γ-irradiation and noise exposure separately. This indicates the presence of synergetic effect of γ-irradiation and noise exposure on auditory function in guinea pigs.
出处
《中国应用生理学杂志》
CAS
CSCD
1991年第4期324-327,共4页
Chinese Journal of Applied Physiology
关键词
辐射
噪声
听力损失
irradiation
noise
hearing loss
interaction
