摘要
目的:对乳腺癌的临床特点及病理特征进行分析。方法:对2012年1月~2017年1月某院收治的180例病理确诊的乳腺癌患者临床资料,总结本组患者的临床特点,剖析病理表现。结果:本组180例患者均为女性,发病年龄(49.5±3.4)岁;首发症状是乳腺肿块,病理确诊时间为(10.5±1.8)个月;肿瘤直径(3.10±0.14)cm;主要是浸润性导管癌,占比90.6%,转移率达到58.5%,以同侧腋下淋巴结转移为主;雌激素受体(ER)阳性率为45.5%,孕激素受体(PR)阳性率为44.4%,人表皮生长因子受体2(Cerb-B-2)阳性率为81.4%,且Cerb-B-2蛋白表达和ER、PR表达相关。结论:乳腺癌以中老年女性为主要发病群,早期诊断率不高,绝大多数就诊时是浸润癌,且部分已转移,所以要早发现、早诊疗。
Objective:To analyze the clinical and pathological characteristics of breast cancer.Methods:The clinical data of 180 patients with pathologically confirmed breast cancer treated in a hospital from January2012 to January 2017 were analyzed.Results:180 patients were female,the age of onset was(49.5±3.4);The first symptom was breast mass,the time of pathological diagnosis was(10.5±1.8)months,the diameter of tumor was(3.10±0.14)cm;It was mainly invasive ductal carcinoma,accounting for 90.6%,and the metastasis rate was 58.5%,mainly ipsilateral axillary lymph node metastasis;The positive rate of ER and PR was 45.5% and 44.4%,respectively.The positive rate of human epidermal growth factor receptor 2 Cerb-B-2 was 81.4%,and the expression of Cerb-B-2 protein was correlated with the expression of ERP and PR.Conclusion:Breast cancer mainly occurs in middle-aged and elderly women,the early diagnosis rate is not high,the vast majority of patients are invasive cancer,and part of the metastasis,so it should be found,diagnosed,and treated early.
出处
《数理医药学杂志》
2018年第2期167-169,共3页
Journal of Mathematical Medicine
关键词
乳腺癌
病理学分析
临床诊断
breast cancer
pathological analysis
clinical diagnosis
