摘要
目的研究假升麻Aruncus sylvester根的化学成分。方法采用大孔树脂、硅胶及反相ODS柱色谱等方法进行分离和纯化,并综合运用NMR、HR-ESI-MS等波谱手段以及ECD计算等方法鉴定化合物的结构。结果从假升麻乙醇提取物正丁醇萃取部分中分离得到2个新的单萜苷,分别鉴定为(2E,4S,5R)-4-hydroxy-3-[2-(β-D-glucopyranosyloxy)ethylidene]-5-(2-methylprop-1-en-1-yl)dihydrofuran-2(3H)-one(1)、(2Z,4S,5R)-4-hydroxy-3-[2-(β-D-glucopyranosyloxy)ethylidene]-5-(2-methylprop-1-en-1-yl)dihydrofuran-2(3H)-one(2)。结论化合物1和2均为新化合物,分别命名为假升麻苷A和假升麻苷B。
Objective To study the chemical constituents from the roots of Aruncus sylvester.Methods The compounds were separated and purified by D101 macroporous resin,silica gel and ODS column chromatography.Their structures were elucidated by extensive spectroscopic methods including 1D and 2D NMR,HR-ESI-MS and ECD spectrum.Results Two new monoterpene glucosides were isolated from A.sylvester,and identified as(2E,4S,SR)-4-hydroxy-3-[2-(β-D-glucopyranosyloxy)ethylidene]-5-(2-methylprop-1-en-1-yl)dihydrofuran-2(3H)-one(1)and(2Z,4S,SR)-4-hydroxy-3-[2-(β-D-glucopyranosyloxy)ethylidene]-5-(2-methylprop-1-en-1-yl)dihydrofuran-2(3H)-one(2).Conclusion Compounds 1 and 2 are new compounds,and named as sylvesteroside A and sylvesteroside B,respectively.
作者
马雪姣
栗章彭
苏艳芳
MA Xue-jiao;LI Zhang—peng;SU Yan—fang(Tianjin Key Laboratory for Modern Drug Delivery and High—Efficiency,School of Pharmaceutical Science and Technology,Tianjin University,Tianjin 300072,China)
出处
《中草药》
CAS
CSCD
北大核心
2018年第2期274-277,共4页
Chinese Traditional and Herbal Drugs
关键词
假升麻属
假升麻
单萜苷
假升麻苷A
假升麻苷B
A runcus Adans.
Aruncus sylvester Kostel.
monoterpene glucoside
sylvesteroside A
sylvesteroside B
