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原发性肺癌癌旁支气管上皮的病理组织学研究

HISTOPATHOLOGICAL STUDY OF THE BRONCHIAL EPITHELIA ADJACENT TO PRIMARY LUNG CANCER
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摘要 本文在49例肺鳞癌癌旁支气管上皮病理检查中,见其病变广泛,且有原位癌形成。35例中心型鳞癌癌旁支气管上皮有明显角化的鳞状上皮化生,且有角化鳞状上皮细胞与癌组织移行部位。提示其参与鳞癌形成,且分化较高。属癌前病变。14例周围型鳞癌中,11例为低分化。癌旁上皮见基底细胞复层增生,异型性明显。提示低分化鳞癌可能不经鳞状化生而由复层增生的基底细胞恶变而来。 The bronchial epithelia being adjacent to carcinoma of the lung in a groupof 49 cases of squamous cell carcinoma and a group of 38 cases of adenocarcinomawere studied histopathologically. On the basis microscopic observations of thesesection of epithelia, stratified hyperplasia of basal cells were related to peripheralpoorly differentiated squamous cell carcinoma of the lung, keratenized squamousmetaplasia were related to central well differentiated squamous cell carcinoma,both of multi-layered hyperplasia of basal cells and keratenized squamous metaplasiawere considered as pre cancerous lesion to squamous cell carcinoma of the lung.
出处 《中国医科大学学报》 CAS CSCD 1991年第1期42-46,共5页 Journal of China Medical University
基金 "七五"攻关课题
关键词 肺癌 鳞状上皮化生 基底细胞增生 basal cell hyperplasia squamous metaplasia keratinization
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参考文献2

  • 1赫明昌,中华病理学杂志,1982年,11卷,3期,188页
  • 2李维华,中华医学杂志,1979年,59卷,10期,616页

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