摘要
目的:分析防治髋、膝关节置换术后深静脉血栓的中药内服处方的用药规律。方法:通过中国知网、重庆维普、万方、中国生物医学文献数据库搜集2001—2016年防治髋、膝关节置换术后深静脉血栓的中药处方,采用TCMISS中医传承辅助平台软件提取分析处方中各药物的使用频次、四气五味归经、归类以及药物之间的关联规则等。结果:对115个中药处方进行分析,使用频率较高的中药有当归、红花、川芎、赤芍、牛膝、桃仁、黄芪、甘草、丹参、白芍、三七、水蛭、生地黄、地龙等。药物的四气分布主要为温、平、凉;五味分布主要为苦、甘、辛;归经分布主要为肝、心、脾。药物归类分布主要为伞形科、菊科、毛茛科。当归、红花、川芎、赤芍、桃仁、黄芪、地龙等均为临床防治髋、膝关节置换术后深静脉血栓最常用的中药。结论:中药防治髋、膝关节置换术后深静脉血栓以益气活血为主要治法,常用处方为补阳还五汤。
Objective： To analyze the medication rule in herbal prescriptions for deep venous thrombosis after total hip or knee replacement. Methods： Herbal prescriptions for deep venous thrombosis after total hip or knee replacement were searched from Chinese National Knowledge Infrastructure, VIP database, Wanfang database and Chinese Biomedical Database, from 2001 to 2016. We used Chinese medicine inheritance support system （TCMISS） to analyze the frequency, four natures, five flavors, meridian entry, plant classification of drugs, and the association rules between drugs. Results： Based on the analysis of 115 herbal prescriptions, herbs used with high frequency were Danggui （Radix Angelicae Sinensis）, Honghua （Flos Carthami）, Chuanxiong （Rhizoma Chuanxiong）, Chishao （Radix Paeoniae Rubra）,Niuxi （Achyranthes）, Taoren （Semen persicae）, Huangqi （Radix As- tragali）, Gancao （Radix Glycyrrhizae）, Dnashen （radix salviae miltiorrhizae）, Baishao （Radix Paeoniae Alba）, Sanqi （pseudo-ginseng）, SShuizhi （leech）, Shengdihuang （rehmannia root） and Dilong （earthworm）, et al. The four na- tures of drugs were mainly consists of warmth, neutral and coolness. The five flavors of drugs were mainly con- sists of bitter, sweet and pungent. Meridian entrys mainly consist of liver, heart and spleen. Plant classification of drugs mainly consists of Apiaceae, Asteraceae and Ranunculaceae. Danggui （Radix Angelicae Sinensis）, Hongbua （Flos Carthami）, Chuanxiong （Rhizoma Chuanxiong）, Chishao （Radix Paeoniae Rubra）, Taoren （Semen persicae）, Huangqi （Radix Astragali） and Dilong （earthworm） were the most commonly used traditional Chinese Medicine for deep venous thrombosis after total hip or knee replacement. Conclusion： The main principle of treatment for deep venous thrombosis after total hip or knee replacement is benefiting Qi for activating blood circulation. The most commonly used traditional Chinese medicine prescription was Buyang Huanwu Decoction
出处
《中医药导报》
2017年第21期25-27,45,共4页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81473698
No.81273781)
教育部高等学校博士点科研基金项目(20124425110004)
广东省科技计划项目(2011B031700027)
广东省财政厅项目([2014]157号)
广东省中医药管理局项目(20164020)
广东省中医院中医药科学技术研究专项(YK2013B2N19
YN2015MS15)
关键词
髋关节置换
膝关节置换
深静脉血栓
中药
益气活血
hip Replacement
knee Replacement
deep vein thrombosis
traditional Chinese medicine
Benefiting Qi For Activating Blood Circulation
