摘要
S-腺苷甲硫氨酸合成酶(S-adenosylmethionine synthetase,SAMS)是广泛存在于动植物以及微生物体内的胞内酶,催化S-腺苷甲硫氨酸(SAM)的合成。近年来的研究发现SAM除了作为细胞甲基化供体,还参与多胺、乙烯、麦根酸等的生物合成过程。SAMS基因响应多种环境胁迫,且在根发育、果实成熟和植物衰老方面发挥作用。但关于SAMS与环境胁迫下植物激素代谢的联系还缺少深入研究。SAM是乙烯与氰化物合成的前体,氰化物诱导植物的抗氰呼吸,但关于SAMS与抗氰呼吸的关系还没有报道。SAM参与的合成麦根酸,同时麦根酸与植物根系对金属离子的吸收紧密关联,但关于SAMS在金属离子吸收、运输中的作用还缺少强有力的实验证据。本文就SAMS的基因表达规律、蛋白质结构、参与的细胞代谢通路、抗逆生理功能进行综述,并对其与抗氰呼吸、金属离子转运和植物激素之间的偶联进行预测和展望。
S-adenosylmethionine synthetase（SAMS）, as an intracellular enzyme wide-spread in plants, animals and microorganisms, catalyzes the formation of S-adenosylmethionine（SAM）, and plays an important role in polyamine, ethylene and mugineic acid biosynthesis, besides its basic role of the methylation donor. The expression of SAMS gene is regulated by multiple environmental changes, and functions in root development, fruit ripening and plant cell senescence. But in-depth studies about the relationship between SAMS and plant hormone metabolism under environmental stress are still lacking. Ethylene and cyanide are synthesized via the same precursor SAM, and cyanide induces cyanide-resistant respiration; but the relationship between SAMS and cyanide-resistant respiration is not well studied. Mugineic acid is also synthesized from SAM. Mugineic acid is involved in the root uptake of metal ions, but there are few strong experimental evidences about the role of SAMS in the absorption of metal ions. In this review, we have summarized SAMS gene expression pattern, the protein structure, the participation in multiple cellular metabolism processes and its functions in plant＇s stress tolerance. The relationships between SAMS and cyanide-resistant respiration, metal ion transports and plant hormones are summarized and prospected.
作者
周琦
郑幸果
何辉煌
康杰
肖海华
ZHOU Qi ZHENG Xingguo HE Huihuang KANG Jie XIAO Haihua(College of Resources, Sichuan Agricultural University, Chengdu 611130, China)
出处
《生命的化学》
CAS
CSCD
2017年第4期521-527,共7页
Chemistry of Life
基金
国家自然科学基金项目(31372052)
关键词
S-腺苷甲硫氨酸合成酶
逆境胁迫
蛋白质结构
乙烯-氰化物合成
多胺合成
S-adenosylmethionine synthetase
environmental stress
protein structure
ethylene-cyanide biosynthesis
polyamine biosynthesis
