摘要
目的探讨清远地区4696例妇科门诊和体检中心就诊人群人乳头瘤病毒的感染状况和基因亚型的分布特征。方法采用HPV-DNA核酸分子快速杂交基因分型方法对就诊妇女的阴道分泌物进行HPV DNA分型检测。结果在4696名妇女中,检测出阳性的患者有831例,阳性率为17.70%,其中有342人感染两种及两种以上亚型,主要以高危型HPV感染为主。HPV 52和HPV 16是最常见的感染亚型,在感染者中分别占25.5%和13.5%。妇科门诊就诊的高危人群组的HPV感染率为20.25%,较体检组感染率12.63%高。各年龄阶段HPV感染率比较,差异无统计学意义(P>0.05)。结论清远地区女性HPV的感染率为17.7%,且以高危型感染为主,其中最为常见的感染亚型为HPV 52。
Objective To investigate the infection status and gene subtype distribution of HPV in 4696 cases of gynecological outpatients and physical examination centers in Qingyuan. Methods HPV DNA typing test was performed by using the HPV-DNA nucleic acid molecule fast hybridization method to detect the vaginal secretions of women. Results In 4,696 women,831 were positive, with a rate of 17.70%.In addition,there were 342 women infected with two or more subtypes,which mainly in high-risk HPV infection.HPV 52 and HPV 16,the most common subtypes,accounted for 25.5% and 13.5% respectively in these people.The rate of HPV infection in the high-risk group was 20.25%,higher than that in the physical examination group （12.63%）.There were no statistically significant differences in HPV infection rates among the various age groups（P〉0.05）. Conclusion The infectious rate of female HPV in Qingyuan area was 17.7%,mainly in high-risk infection type.The most common infection subtype was HPV 52.
出处
《中国医药科学》
2017年第20期20-23,共4页
China Medicine And Pharmacy
