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广州地区宫颈癌组织标本中HPV感染情况的初步分析 被引量：14

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摘要 目的探讨广州地区宫颈癌患者人乳头瘤病毒(HPV)感染及其型别分布。方法采用HPV通用引物对宫颈癌组织标本中的HPVL1区基因序列进行PCR扩增,根据PCR产物测序所得序列分析对HPV分型。结果130例宫颈癌组织HPVDNA检出率为82.3%,广州宫颈癌患者存在HPV16、33、18、52、11、31、58、68、53和59十种型别。结论证实了生殖道高危型HPV感染是妇女宫颈癌发病的重要因素。
作者 曾莉 郭遂群 云径平 谢波 俞守义
机构地区 南方医科大学公共卫生与热带医学学院 南方医科大学南方医院妇产科 中山大学附属肿瘤医院病理科 广东省第二中医院妇产科
出处 《南方医科大学学报》 CAS CSCD 北大核心 2007年第3期399-400,共2页 Journal of Southern Medical University
关键词 人类乳头瘤病毒 宫颈癌 聚合酶链反应 测序分析
分类号 R737.33 [医药卫生—肿瘤]
  • 相关文献

参考文献11

  • 1Bosh FX,Rohan T,Schnieder A,et al.Papillomavirus research update:highlights of the Barcelona HPV 2000 international papillomavirus conference[J].J Clin Pathol,2001,54(3):163-75.
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二级参考文献15

  • 1Peter J F, Adriaan J C, Chris J L, et al. The clinical relevance of human papillomavirus testing: relationship between analytical and clinical sensitivity[J]. J Pathol, 2003,201:1 - 6.
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共引文献55

同被引文献170

引证文献14

二级引证文献295

南方医科大学学报
2007年 第3期

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