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一种蛹虫草固体饮料对小鼠肠道菌群的影响 被引量:5

Effect of a Kind of Cordyceps militaris Solid Beverage on the Intestinal Flora of Mice
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摘要 [目的]研究蛹虫草速溶粉(佑元茶)对小鼠肠道菌群的影响。[方法]利用抗生素(青霉素钠)构建肠道菌群失调小鼠模型,以正常小鼠为对照,采用菌落计数法考察一种蛹虫草固体饮料对肠道菌群失调小鼠的肠道修复作用。[结果]蛹虫草固体饮料的高、中剂量组小鼠的体重显著高于其他组(P<0.05)。高、中、低3个剂量组小鼠肠道中的益生菌乳酸杆菌和双歧杆菌数量均显著高于模型组,且条件致病菌肠球菌数量均显著少于模型组(P<0.05);3个剂量组中,中、高剂量组与低剂量组间亦存在显著性差异(P<0.05),但中高剂量组间差异不明显。[结论]蛹虫草固体饮料对于抗生素干扰引起的肠道菌群失调具有较好的修复作用,可调节并保持肠道微生态菌群的平衡。 [Objective]The research aimed to study the the effect of a kind of Cordyceps militaris instant powder( Youyuan tea) on the intestinal flora of mice. [Method] Antibiotics( penicillin sodium) was used to build the alteration of intestinal flora illness model of mice,the normal mice were used as control and the colony counting method was used to explore the effect of a kind of Cordyceps militaris solid beverage on the intestinal flora of mice. [Result]The weight of mice in high and medium dose group was higher than other groups dramatically( P〈0. 05).The quantity of probiotics such as lactobacillus and bifidobacterium in the mice intestinal canal of dose groups was higher than that of model group,and the quantity of conditioned pathogen such as enterococcus was lower than the model group( P〈0. 05); there was a significant difference existed among the low dose group and the middle,high dose group,but the difference between middle and high dose groups was not obvious. [Conclusion] The Cordyceps militaris solid beverage has better recovery effect on the alteration of intestinal flora which was caused by antibiotics,and it also could adjust and maintain the balance of intestinal microecology.
出处 《安徽农业科学》 CAS 2017年第29期124-125,143,共3页 Journal of Anhui Agricultural Sciences
基金 江苏省科技计划项目(BN2016003 BE2017352 BN2015012) 江苏省高校自然科学研究重大专项(15KJA180008)
关键词 蛹虫草 固体饮料 抗生素 肠道菌群 Cordyceps militaries Solid beverage Antibiotics Intestinal flora
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