摘要
目的通过检测脑卒中患者血浆纤维蛋白原水平(FIB),探讨脑卒中与血浆FIB之间的关系。方法健康对照组90例,脑卒中组128例,采用氧化酶法检测空腹血糖(FBG)、总胆固醇(TCH)和甘油三酯(TG),采用凝固酶法检测FIB,采用高效液相色谱法检测糖化血红蛋白(Hb A1c)。结果脑卒中组血浆FBG、TG、Hb A1c、FIB水平与对照组比较,差异有统计学意义(P<0.01)。通过多因素条件Lobistic逐步回归分析,血浆FIB、TG、FBG和Hb A1c是脑卒中的独立危险因素。结论脑卒中患者血浆FIB浓度显著增高,可作为临床判断脑卒中发生的独立危险因素。
Objective to study the relationship between the plasma fibrinogen and stroke by testing plasma fibrinogen levels in patients with stroke.Methods The fasting blood glucose （ FBG）, total cholesterol （TCH） and triglyceride （TG） in the healthy group （90 cases） and stroke group （128 cases） were detected by oxidase method.The FIB was detected by coagulase method and glycosylated red blood protein （HbAlc） was detected by high performance liquid chromatography （HPLC）.Results The difference of FBG,TCH ,TG, HbA1c and plasma FIB levels in the two groups were statistically significant （ P 〈0.01）.The plasma FIB,TG, FBG and HbAlc were independent risk factors for stroke by multivariate conditional Lobistic stepwise regression analysis. Conclusion The plasma FIB concentration was significantly increased in patients with stroke,which could be used as an independent risk factor for the clinical evaluation of stroke.
出处
《湖北民族学院学报（医学版）》
2017年第3期8-9,13,共3页
Journal of Hubei Minzu University(Medical Edition)
