摘要
目的评价分析复方消化酶、莫沙必利联合胃苏颗粒治疗功能性消化不良的临床效果。方法将2014年7月至2016年7月在我院进行治疗的150例功能性消化不良患者纳入本次研究,随机分为对照组70例和观察组80例。对照组患者采用枸橼酸莫沙必利片进行治疗,观察组患者在对照组基础上,联合复方消化酶、胃苏颗粒进行治疗,比较两组患者的临床治疗效果、症状积分、复发及不良反应情况。结果经不同治疗后,观察组总有效率(96.75%)高于对照组(74.29%),差异有统计学意义(P<0.05);观察组患者各项临床症状积分低于对照组,差异有统计学意义(P<0.05);两组的不良反应率差异无统计学意义(P>0.05);观察组的疾病预后复发率(2.50%)明显低于对照组(24.29%),差异有统计学意义(P<0.05)。结论采取复方消化酶、莫沙必利联合胃苏颗粒治疗功能性消化不良,可显著改善患者各类临床不良症状,治疗期间头晕、口干、皮疹、便秘等不良反应少,预后复发率低,与单独应用莫沙必利相比,临床效果更佳。
Objective To evaluate the effect of compound digestive enzyme,mosapride combined with Weisu granule in the treatment for 80 cases patients with functional dyspepsia.Methods A total of 150 patients with functional dyspepsia in our hospital from July 2014 to July 2016 were included in this study.They were divided into observation group and control group randomly.70 patients in control group were treated by mosapride citrate tablets,80 patients in the observation group were given compound digestive enzyme combined with Weisu granule for treatment on the basis of control group.The clinical curative effect,symptom score,recurrence and adverse reaction of two groups were compared.Results After different treatment,the total efficiency of the observation group（96.75%）was significantly higher than that in the control group（74.29%）（P〈0.05）.All the clinical symptom scores in the observation group were statistically lower compared with the control group（P〈0.05）.There was no difference of the adverse reactions in the two groups（P〉0.05）.The recurrence rate of the disease in the observation group（2.50%）was significantly lower than that in the control group（24.29%）,and the difference was statistically significant（P〈0.05）.Conclusion Compound digestive enzyme,mosapride combined with Weisu granule in the treatment for functional dyspepsia can significantly improve the clinical symptoms and there has less adverse reactions such as dizziness,dry mouth,rash and constipation during the treatment,and the recurrence rate is low.It has a better clinical effect compared with the single application of mosapride.
出处
《青岛医药卫生》
2017年第4期260-263,共4页
Qingdao Medical Journal
