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带状疱疹患者血清神经元特异性烯醇化酶水平的变化及意义 被引量:10

Change and significance of serum neuron specific enolase level in patients with herpes zoster
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摘要 目的比较带状疱疹患者治疗前后血清神经元特异性烯醇化酶(NSE)水平的变化。方法测定100例带状疱疹患者(观察组)治疗前后和100例健康体检者(对照组)的血清神经元特异性烯醇化酶(NSE)水平。结果观察组治疗前NSE水平显著高于对照组(P<0.01)。观察组治疗前血清NSE水平显著高于治疗后(P<0.01)。观察组中NSE水平在不同皮损部位、范围及疼痛程度间存在显著差异(P<0.05)。结论带状疱疹患者急性期NSE水平升高,且与皮损范围、发病部位、疼痛程度相关。 Objective To compare the serum euron specific enolase( NSE) level before and after treatment in patients with herpes zoster. Methods The serum level of NSE were measured in 100 patients with herpes zoster( observation group) before and after treatment and 100 healthy controls( control group). Results Level of NSE before treatment in observation group was significantly higher than that after treatment and that in control group( P〈0. 01). There were significant differences in NSE levels between patient with different location,extent and degree of pain( P〈0. 01).Conclusion Serum NSE level increases significantly in patients with acute herpes zoster,and the NSE level is correlated with the range of skin lesions,the location of the disease and the degree of pain.
出处 《实用临床医药杂志》 CAS 2017年第13期100-102,共3页 Journal of Clinical Medicine in Practice
基金 黑龙江省政府博士后科研基金项目(CBH-Z12254)
关键词 带状疱疹 神经元特异性烯醇化酶 检测 herpes zoster neuron specific enolase detection
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