摘要
笔者在系统的文献调研基础上,对绞股蓝的化学成分和药理作用研究进展进行总结。绞股蓝中主要含达玛烷型皂苷,1976年至2011年共分离得到165个绞股蓝皂苷。近几年又有新的绞股蓝皂苷陆续被分离鉴定,笔者对已明确结构的共201个绞股蓝皂苷进行分类总结。另外,绞股蓝中还含有黄酮、多糖、氨基酸和微量元素等多种化学成分,值得深入研究和关注。此外,总结了绞股蓝抗肿瘤、调节血脂、降血糖、保护肝脏、抗衰老和提高免疫力等药理活性,旨在为绞股蓝的进一步研究提供参考。
This paper summarized the chemical constituents and pharmacological activities of C, ynostemma pentaphyllum based on systematic literature research. G. pentaphyllum mainly contains dammarane-type saponins and a total of 165 gynostemma saponins were obtained from 1976 to 2011. In recent years, some new gypenosides were isolated and identified. Two hundred and one gypenosides were classified and summarized in this paper. In addition, G. pentaphyllum also contains a variety of other chemical components inclu- ding flavonoids, polysaccharides, amino acids, and trace elements, which are worth further research. The pharmacological effects of G. pentaphyllum including antitumor, regulating blood lipid, hypoglycemie, fiver protection, anti-senility and improving immunity effects were summarized. This review will provide some information for further research of G. pentaphyllum.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2017年第5期342-352,共11页
Chinese Pharmaceutical Journal
关键词
绞股蓝
皂苷
药理作用
Gynostemma pentaphyllum
saponin
pharmacological action
