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绞股蓝皂甙对糖尿病大鼠降糖作用的观察 被引量:15

Effect of gypenosides on the levels of fasting plasma glucose in diabetic rats
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摘要 观察绞股蓝皂甙对链脲佐菌素造模的糖尿病大鼠血糖的影响。结果发现绞股蓝皂甙治疗4周后,糖尿病大鼠空腹血糖、胰岛素、血清甘油三酯、总胆固醇水平、血清过氧化脂质含量均比对照组明显降低,血清超氧化物歧化酶活性明显升高。提示绞股蓝皂甙具有降糖、降脂及可能有抗氧化作用。 The effects of gypenosides (Gps) on the levels of fasting plasma glucose (FPG),fasting in- sulin (INS),total cholesterol(TC),triglyceride (TG),serum lipid peroxide (LPO) value and serum super- oxide dismutase (SOD) activity in STZ-induced diabetic rats were studied.The levels of FPG、INS、TC、TG and serum LPO value were decreased while serum SOD activity was increased significantly in diabetic rats after four weeks of Gps treatment in comparison with those in control rats.These results suggest that Gps have the effects of decreasing the levels of blood sugar,lipid and possibly scavenging free radicals.
出处 《中国糖尿病杂志》 CAS CSCD 1997年第4期229-230,共2页 Chinese Journal of Diabetes
关键词 绞股蓝皂甙 糖尿病 降糖作用 药理学 Gypenosides Superoxide dismutase
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