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微创髓芯减压植入CPC复合BMP治疗ARCOⅡ-Ⅲb期成人股骨头坏死的疗效观察 被引量:3

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摘要 目的探讨ARCOⅡ-Ⅲb期成人股骨头坏死微创治疗方法。方法2012年1月至2015年3月ARCOⅡ-Ⅲb期成人股骨头坏死患者9例(14个髋),采用影像导引下的微创髓芯减压,应用磷酸钙骨水泥(CPC)复合骨形态生成蛋白(BMP)作为植入物,填充替代股骨头坏死区域的坏死骨组织,采用Harris髋关节功能评分和影像学评价,进行临床疗效综合评估。结果分别于术后6个月及12个月各随访1次.其后不定期随访,随访最长3年。术前Harris评分平均84.50分,术后末次随访平均91-36分,差异有统计学意义。术后影像学末次评估14个股骨头塌陷1个,未塌陷13个,其中坏死面积无变化8个,面积缩小5个;水肿消退或范围缩小10个,无明显变化者3个,加重1个。结论髓芯减压结合磷酸钙骨水泥+BMP治疗ARCOⅡ-Ⅲb期成人股骨头坏死能明显改善患者症状和髋关节功能,预防股骨头塌陷或防止股骨头进一步塌陷,临床疗效满意。 Objective The minimally invasive treatment of femoral head necrosis in adults with ARCOⅡ-Ⅲb. Methods Collected from January 2012 to March 2012, a total of nine patients ( 14 hips ) with ARCOⅡ-Ⅲb adult femoral head necrosis, with Image - guided minimally invasive core decompression, marrow needle relief application of calcium phosphate cement ( CPC ) composite BMP as implants, filled replacement tissue necrosis area of femoral head necrosis, used preoperative Harris hip function score and postoperative radiographic evaluation, for the comprehensive assessment of clinical curative effect. Results The patients were followed up for 6 months and 12 months respectively. The patients' longest follow-up period was 3 years. The average Harris score was 84.50 points before operation, and the average follow-up was 91.36 points at the end of the operation, and there was statistical significance between the preoperative and postoperative (P〈0.05) . In last postoperative radiographic assessment, there was 1 femoral head collapse,13 did not collapse, 8 necrotic area, 5 necrotic area no change, 10 edema, fade or narrow, 3 no obvious change, 1 aggravation. Conclusion Imramedullary needle decompression combined with phosphate calcium phosphate cement BMP treatment ARCOⅡ-Ⅲb period of adult femoral head necrosis can obviously improve the symptoms and the function of hip joint and prevent femoral head collapse or prevent further femoral head collapse, curative effect is satisfactory.
出处 《浙江临床医学》 2017年第3期464-465,468,共3页 Zhejiang Clinical Medical Journal
基金 浙江省金华市科技计划项目(2013-3-049)
关键词 股骨头坏死 微创 髓芯减压 磷酸钙骨水泥 骨形态生成蛋白 Osteonecosis of the femoral head Minimally invasive Marrow needle relief Calcium phosphate cement BMP
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  • 1赵德伟,王卫明,王本杰,王铁男,芦健民,郭林,崔旭,于晓光.保留股骨头手术治疗股骨头缺血性坏死1005例临床分析[J].中华外科杂志,2005,43(16):1054-1057. 被引量:52
  • 2张长青,曾炳芳,眭述平,袁霆,徐铮宇,邵雷,李鸿帅,张开刚.改良吻合血管游离腓骨移植治疗股骨头缺血性坏死的手术技术[J].中国修复重建外科杂志,2005,19(9):692-696. 被引量:46
  • 3王正,黄相杰,姜红江.股骨头缺血性坏死的髓芯减压及其相关研究进展[J].中医正骨,2006,18(10):78-79. 被引量:7
  • 4许本柯,徐达传,王兵,刘行坦,刘萍.股骨头血供特点及临床意义[J].解剖学杂志,2007,30(3):371-373. 被引量:13
  • 5Cheng EY. Thongtrangan I, Laorr A, et al. Spontaneous resolution of osteoecrosis of the femoral head. J Bone Joint Sorg(Am). 2004, 86(11): 2594-2599.
  • 6Mont MA, Carbone J J, Fairbank AC. Core decompression versus non-operative management for osteonecrosis of the hip. Clin Orthop Relat Res, 1996(324): 169-178.
  • 7Garino JP, Steinberg ME. Total hip arthroplasty, inpatient with avaseular necrosis of tile femoral head. Clin Orthop Relat Res. 1997(334): 108-115.
  • 8Wang GJ, Cui Q, Balian G. The pathogenesis and prevenlion of steroid induced osteonecrosis. Clin Orthop Relat Res, 2000(370): 295-310.
  • 9Pritchett .JW. Statin therapy decreases the risk of osteonecrosis inpatiens receiving steroids. Ctin Orthop Relat Res, 2001 (396): 173-178.
  • 10Glueck C J, Freiberg R, Glueck HI, et al. Idiopathic osteonecrosis, hypofibrinolysis, high plasminogen activator inhibitor, high lipoprotein and therapy with Stanozolol. Am J Hematol, 1995, 48 (4): 213-220.

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