摘要
布鲁菌病是由布鲁菌引起的具有传染性的变态反应性人畜共患病。人类患病的主要原因是接触未经巴氏消毒的牛、羊、猪等布氏杆菌携带或感染者。布鲁菌通过人类的皮肤、呼吸道和消化道进入体内,寄生繁殖并入血,释放内毒素,导致人体发热及多器官损伤。Kulowski于1932年首次描述布鲁菌病可引起脊柱炎。有学者提出布鲁菌病最常伴发脊柱炎,主要累及腰椎。现将研究布氏杆菌性脊柱炎的诊断,尤其是治疗方案作如下综述。
Brucellosis is an infectious and allergic zoonosis caused by bacteria of the genus Brucella. Spondylitis, especially lumbar spondylitis, is the most common complication of brucellosis. It is difficult to diagnose brucellar spondylitis. And there are some controversies in the treatment method. M ost of researchers suggest that we can make a definitive diagnosis through epidemiological contact history, clinical assessment, image features, serum agglutination test and blood culture. Once brucellar spondylitis is confirmed, combination antibiotic therapy with adequate duration should be used and surgical intervention is determined by the degree of infection. In this review, we focus on the diagnosis, and especially the treatment method of brucellar spondylitis.
作者
吕永威
李利
LU Yong-wei LI Li(Department of Orthopedics, the first Affiliated Hospital of PLA General Hospital, Beijing, 100048, PRC)
出处
《中国骨与关节杂志》
CAS
2016年第11期847-850,共4页
Chinese Journal of Bone and Joint
关键词
脊柱炎
布鲁杆菌病
诊断
药物疗法
外科手术
Spondylitis
Brucellosis
Diagnosis
Drug therapy
Surgical procedures
operative
