摘要
目的探讨经导管介入与经胸小切口封堵术治疗小儿动脉导管未闭(PDA)的临床价值差异。方法选取2012年8月-2014年8月在该院接受治疗的PDA患儿108例作为研究对象,根据接受的治疗方式不同,分为接受经胸小切口封堵术治疗的对照组(58例)和接受导管介入治疗的观察组(50例)。对比两组患儿的手术相关指标、肺动脉压、血清肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白(c Tn T)水平,以及术后并发症发生率等的差异。结果观察组患儿治疗后术中失血量少于对照组,手术时间、重症加强护理病房住院时间、住院总时间均短于对照组患儿,差异有统计学意义(P<0.05);观察组患儿治疗后肺动脉收缩压、肺动脉舒张压均低于对照组,血清CK-MB、c Tn T水平低于对照组患儿,差异有统计学意义(P<0.05);观察组患儿治疗后封堵器脱落、心脏穿孔、心律失常、残余分流等并发症发生率低于对照组患儿,差异有统计学意义(P<0.05)。结论 PDA患儿接受经导管介入治疗,可以优化手术过程并提升治疗效果,心肌组织损伤小,术后并发症少,是治疗PDA的首选方法。
Objective To discuss the difference between transcatheter occlusion and transthoracic mini- incision occlusion for children with patent ductus arteriosus. Methods A total of 108 children with patent ductus arteriosus between August 2012 and August 2014 in our hospital were chosen as research subjects. They were divided into control group （n = 58） with transthoracic mini-incision occlusion and observation group （n = 50） with transcatheter occlusion. The patients of the two groups were compared in surgery related indica- tors, pulmonary artery pressure, serum CK-MB and cTnT levels, and incidence of postoperative complications. Results Compared to the control group, the blood loss was less, the operative time, duration of ICU stay and total hospitalization time were shorter in the observation group after treatment, the differences were statistically significant （P〈 0.05）. The pulmonary artery systolic pressure and diastolic blood pressure, and serum CK-MB and cTnT levels in the observation group were significantly lower than those in the control group （P 〈 0.05）. The rates of complications in the observation group such as occluder off, cardiac perforation, cardiac arrhyth- mia and residual shunt were significantly lower than those in the control group （P 〈 0.05）. Conclusions When transcatheter intervention therapy is applied for patients with patent ductus arteriosus, the surgical procedure can be optimized, and the therapeutic effect can be improved, with little myocardial damage and few compli- cations. Therefore, it is a great method for treatment of patent ductus arteriosus.
出处
《中国现代医学杂志》
CAS
北大核心
2016年第21期79-82,共4页
China Journal of Modern Medicine
关键词
动脉导管未闭
经导管介入
经胸小切口封堵术
patent ductus arteriosus
transcatheter intervention
transthoracic mini-incision
