摘要
这里发现锰化合物能够催化芳香碳-氧键的还原断裂.就我们所知,目前还没有锰催化芳香碳-氧键断裂方面的报道.以二苯并呋喃为底物,对各种反应条件进行优化,得到的较佳反应条件为5%Mn(OAc)_2,3当量LiAlH 4,140℃温度,四氢呋喃溶剂.在这个反应条件下,多种芳香碳-氧键能够发生还原断裂.甲醇钠的添加能够有效地促进二苯醚等底物的反应.对反应机理进行了初步研究,结果表明反应可能经历自由基过程.
Manganese compounds were found to be effective to catalyze the reductive cleavage of carbon-oxygen bonds. To the best of our knowledge, no effective Mn-based catalyst was reported for this process. The reaction conditions were optimized by choosing dibenzofuran as the substrate, and the obtained optimum conditions were as follows： 5% Mn （OAc）2, 3 equiv. LiAlH4, 140℃ as the reaction temperature, THF as the solvent. The optimum conditions allowed a series of aromatic carbon-oxygen bonds to undergo the reductive cleavage. An addition of sodium methoxide was beneficial for the reaction of some substrates including diphenyl ethers. Preliminary mechanistic investigation suggests that the present reaction possibly undergoes a radical pathway.
出处
《分子催化》
EI
CAS
CSCD
北大核心
2016年第5期401-408,共8页
Journal of Molecular Catalysis(China)
基金
sponsored by the Open Project of State Key Laboratory for Oxo Synthesis and Selective Oxidation(Grant No.OSSO-2015-21)
the Program for Science&Technology Innovation Talents in Universities of Henan Province(Grant No.15HASTIT004)
关键词
还原断裂
碳-氧键
锰
催化
reductive cleavage
carbon-oxygen bond
manganese
catalysis
