摘要
COPD是一种异质性明显的疾病。目前COPD大体分为8个表型:临床表型、生理表型、影像学表型、COPD频发急性加重表型、全身炎症表型、合并症表型、多维指数测评表型和ACOS表型。COPD急性加重(AECOPD)是影响疾病发病率、病死率、生活质量、医疗费用的最主要因素。本文就COPD各种表型与AECOPD之间相关性的研究进展进行总结。
Chronic obstructive pulmonary disease(COPD)is a heterogeneous disease obviously. Recently, COPD phenotypes may generally divide into eight subtypes: clinical phenotype, physiological phenotype, radiologic phenotype, acute exacerbations of COPD phenotype, systemic inflammatory phenotype, complication phenotype, multidimensional index evaluation phenotype, ACOS phenotype. AECOPD are the cardinal factor associated with mortality, morbidity, impaired quality of life and healthcare costs in the disease. This review focuses on discussing the association between different COPD phenotypes and AECOPD.
出处
《国际呼吸杂志》
2016年第19期1498-1503,共6页
International Journal of Respiration
关键词
慢性阻塞性肺疾病
表型
急性加重
Chronic obstructive pulmonary disease
Phenotype
Acute exacerbation